Park Nicollet Clinic Department of Internal Medicine, International Diabetes Center, HealthPartners Institute, MN, USA.
Research and Education Department, CGParkin Communications, Inc, Henderson, NV, USA.
Postgrad Med. 2022 Aug;134(6):576-588. doi: 10.1080/00325481.2022.2080419. Epub 2022 May 27.
A significant proportion of individuals with diabetes have suboptimal glycemic management. Studies have shown that persistent hyperglycemia significantly increases the risks for both acute and long-term microvascular and macrovascular complications of diabetes. A key contributor to suboptimal glycemic management is therapeutic inertia in which clinicians delay intensifying therapy when patients are not meeting their glycemic goals. During the past five years, an increasing number of individuals with type 1 diabetes (T1D) and insulin-treated type 2 diabetes (T2D) have adopted the use of continuous glucose monitoring (CGM) for daily measurement of glucose levels. As demonstrated in numerous clinical trials and real-world observational studies, use of CGM improves glycated hemoglobin (HbA1c) and reduces the occurrence and severity of hypoglycemia. However, for primary care clinicians who are unfamiliar with using CGM, integrating this technology into clinical practice can be daunting. In this article, we discuss the benefits and rationale for using CGM compared with traditional blood glucose monitoring (BGM), review the evidence supporting the clinical value of CGM in patients with T1D and T2D, and describe how use of CGM in primary care can facilitate appropriate and more timely therapy adjustments.
相当一部分糖尿病患者的血糖控制不理想。研究表明,持续的高血糖显著增加了糖尿病急性和长期微血管和大血管并发症的风险。血糖控制不理想的一个主要原因是治疗惰性,即当患者的血糖目标未达到时,临床医生延迟加强治疗。在过去五年中,越来越多的 1 型糖尿病(T1D)和接受胰岛素治疗的 2 型糖尿病(T2D)患者采用连续血糖监测(CGM)来日常测量血糖水平。正如许多临床试验和真实世界观察研究所示,使用 CGM 可改善糖化血红蛋白(HbA1c)水平,并减少低血糖的发生和严重程度。然而,对于不熟悉使用 CGM 的初级保健临床医生来说,将这项技术整合到临床实践中可能会令人生畏。在本文中,我们讨论了与传统血糖监测(BGM)相比使用 CGM 的益处和基本原理,回顾了支持 CGM 在 T1D 和 T2D 患者中临床价值的证据,并描述了 CGM 在初级保健中的使用如何促进更合适和更及时的治疗调整。