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真是一团糟!基底神经节着火了。

Great balls of fire! The basal ganglia on fire.

机构信息

Aster Medcity, Kochi, India.

出版信息

Clin Med (Lond). 2022 May;22(3):276-277. doi: 10.7861/clinmed.2022-0038.

Abstract

A 76-year-old man presented to the hospital with intermittent dizziness, memory impairment and jerky movements. Evaluation revealed them to be faciobrachial dystonic seizures and antibodies to voltage-gated potassium channel complexes were found. He was treated with intravenous methylprednisolone and rituximab, and made a remarkable recovery. Magnetic resonance imaging of the brain was normal, although positron emission tomography - computed tomography showed striking basal ganglia changes.

摘要

一位 76 岁男性因间歇性头晕、记忆力减退和抽搐样运动就诊于医院。评估发现这些表现为面肩肱型肌张力障碍发作,且检测到电压门控钾通道复合物抗体。患者接受了静脉注射甲基强的松龙和利妥昔单抗治疗,病情显著改善。脑部磁共振成像正常,但正电子发射断层扫描-计算机断层扫描显示基底节明显改变。

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本文引用的文献

1
The Clinical Value of F-FDG-PET in Autoimmune Encephalitis Associated With LGI1 Antibody.
Front Neurol. 2020 Jun 5;11:418. doi: 10.3389/fneur.2020.00418. eCollection 2020.
2
The importance of early immunotherapy in patients with faciobrachial dystonic seizures.
Brain. 2018 Feb 1;141(2):348-356. doi: 10.1093/brain/awx323.
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Autoimmun Rev. 2016 Oct;15(10):970-4. doi: 10.1016/j.autrev.2016.07.018. Epub 2016 Jul 30.
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Faciobrachial dystonic seizures precede Lgi1 antibody limbic encephalitis.
Ann Neurol. 2011 May;69(5):892-900. doi: 10.1002/ana.22307. Epub 2011 Mar 17.

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