From the Department of Brain and Behavioral Sciences (M. Avenali, G.V., R.D.I., A.P., R.B., C.T.), University of Pavia; and Neurorehabilitation Unit (M. Avenali, G.V., R.D.I., V.G., C.S., C.G., A.P., R.B., M. Allena, C.T.), IRCCS Mondino Foundation, Pavia, Italy.
Neurology. 2022 Jul 11;99(2):77-81. doi: 10.1212/WNL.0000000000200714.
We report a case of a 60-year-old patient with a 10-year history of Parkinson disease who developed a dyskinetic-dystonic gait pattern highly affecting his personal and social life. After multiple unsuccessful attempts to improve the clinical condition by adapting the pharmacologic treatment, the patient underwent gait rehabilitation based on the use of visual cueing. This approach induced a relevant improvement in the dyskinetic-dystonic gait. Our case contributes to the phenotypic description of motor fluctuations in advanced Parkinson disease and suggests an additional therapeutic option to mitigate their impact on motor performances.
我们报告了一例 60 岁的帕金森病患者,他有 10 年的病史,出现了严重影响个人和社会生活的运动障碍-肌张力障碍步态模式。在多次尝试通过调整药物治疗来改善临床状况但均未成功后,患者接受了基于视觉提示的步态康复治疗。这种方法显著改善了运动障碍-肌张力障碍步态。我们的病例有助于描述晚期帕金森病中运动波动的表型,并为减轻其对运动表现的影响提供了另一种治疗选择。