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帕金森病中左旋多巴诱发异动症的“提示”

"Cueing" for Levodopa-Induced Dyskinesias in Parkinson's Disease.

作者信息

Schaeffer Eva, Linke Gerd, Berg Daniela

机构信息

Department of Neurology, Christians-Albrechts-University of Kiel , Kiel , Germany.

ZAR, Department for Physical Therapy, University of Tuebingen , Tuebingen , Germany.

出版信息

Front Neurol. 2016 Dec 23;7:237. doi: 10.3389/fneur.2016.00237. eCollection 2016.

Abstract

We describe the case of an early-onset Parkinson's disease (PD) patient, suffering from a severe and unusual dyskinetic gait pattern, earlier described as "Silly walk." On presentation, the 58-year-old patient showed a painful, bizarre dyskinetic gait disorder, resulting in a significantly impairment of her social life. We developed an individual conservative training method for the patient, using "Cueing mechanisms," well known for treatment of Freezing in PD, to overcome her dyskinetic gait pattern. An impressive improvement was seen after the use of visual and acousting cues. We, therefore, conclude that it might be important for PD patients to recognize these specific movement abnormalities and start early with individualized training methods. Moreover, especially for "Silly walk" individuals, "Cueing" strategies can be an important new basis of conservative training methods for dyskinesia.

摘要

我们描述了一例早发性帕金森病(PD)患者的病例,该患者患有严重且不寻常的运动障碍性步态模式,此前被描述为“滑稽步态”。初诊时,这位58岁的患者表现出一种疼痛、怪异的运动障碍性步态障碍,严重影响了她的社交生活。我们为该患者制定了一种个性化的保守训练方法,采用了以治疗帕金森病冻结现象而闻名的“提示机制”,以克服她的运动障碍性步态模式。使用视觉和听觉提示后,患者有了显著改善。因此,我们得出结论,帕金森病患者认识到这些特定的运动异常并尽早开始采用个性化训练方法可能很重要。此外,特别是对于“滑稽步态”患者,“提示”策略可能成为运动障碍保守训练方法的重要新基础。

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