Department of Chest Diseases, Adıyaman University, Department of Internal Medicine, Medicine Faculty, Adıyaman, Turkey.
Eur Rev Med Pharmacol Sci. 2022 May;26(9):3361-3366. doi: 10.26355/eurrev_202205_28756.
The aim of the study was to investigate the effect of blood values at first admission to the hospital on predicting mortality in COVID-19 patients hospitalized in the intensive care unit (ICU).
The blood parameters of 284 intensive care patients, who were diagnosed with COVID-19 via the Real-Time Polymerase Chain Reaction (RT-PCR) for SARS-CoV-2 RNA test, at first admission to the hospital, were evaluated. The contribution of these parameters to predicting mortality was analyzed.
No significant relationship was found between complete blood count and mortality. However, it was determined that the ferritin, ALT, D-dimer, and urea levels significantly affected the mortality rates in intensive care patients.
The ferritin, ALT, D-dimer, and urea levels of patients who were admitted to the ICU due to COVID-19, at first admission to the hospital, were significant in predicting mortality. Therefore, it is recommended that these parameters will be evaluated at the first application.
本研究旨在探讨患者首次入院时的血液值对预测因 COVID-19 入住重症监护病房（ICU）的患者死亡率的影响。
评估了 284 名经 SARS-CoV-2 RNA 检测的实时聚合酶链反应（RT-PCR）确诊为 COVID-19 的重症监护患者首次入院时的血液参数。分析了这些参数对预测死亡率的贡献。
全血细胞计数与死亡率之间无显著关系。然而，铁蛋白、ALT、D-二聚体和尿素水平显著影响了重症监护患者的死亡率。
因 COVID-19 入住 ICU 的患者首次入院时的铁蛋白、ALT、D-二聚体和尿素水平对死亡率有显著预测作用。因此，建议在首次就诊时评估这些参数。
