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慢性乙型肝炎筛查指南在中高流行国家人群中的依从性。

Adherence to chronic hepatitis B screening guidelines for persons from intermediate to high prevalence Countries.

机构信息

Internal Medicine Resident, University of Washington Medical Center, 1959 NE Pacific Street, Box 356421, Seattle, USA.

Department of Medicine, Harborview Medical Center, University of Washington School of Medicine, 325 9th Ave Box 359928, Seattle, WA, 98104, USA.

出版信息

J Community Health. 2022 Aug;47(4):704-709. doi: 10.1007/s10900-022-01102-7. Epub 2022 May 19.

Abstract

The adherence to the CDC guideline on screening non-U.S. born persons for hepatitis B virus infection was assessed. A retrospective cohort study was conducted at University of Washington primary care clinics using the electronic medical records. Persons from hepatitis B virus prevalent countries were identified using country of origin and language. Of 2329 eligible for screening, only 617 (26.5%) were screened. The prevalence of HBsAg was 35 (5.7%). Among women of reproductive age (18-44 years, n = 906), 238 (26.3%) were screened, and 7 (2.9%) were HBsAg positive. Low screening practice for chronic hepatitis B infection, and high infection prevalence among those screened was noted. The findings indicate that potentially three out of every one detected case may be missed. Urgent efforts are needed to scale up and consistently implement HBV screening at primary care clinics.

摘要

本研究评估了是否遵循疾病预防控制中心(CDC)关于筛查非美国出生人群乙型肝炎病毒(HBV)感染的指南。该研究采用电子病历,对华盛顿大学初级保健诊所的人群进行了回顾性队列研究。通过原籍国和语言识别 HBV 流行国家的人群。在 2329 名符合筛查条件的人群中,仅有 617 人(26.5%)接受了筛查。HBsAg 的阳性率为 35(5.7%)。在育龄妇女(18-44 岁,n=906)中,有 238 人(26.3%)接受了筛查,7 人(2.9%)HBsAg 阳性。慢性乙型肝炎感染的筛查实践率较低,而接受筛查者的感染率较高。这些发现表明,每检测到的三个病例中可能就有一个漏诊。迫切需要加大力度,在初级保健诊所持续实施 HBV 筛查。

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