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慢性治疗抵抗性双侧夏科氏足骨关节炎伴骨髓炎迹象的挽救治疗

Salvage of Chronic Therapy-Resistant Bilateral Charcot Foot Osteoarthropathy with Signs of Osteomyelitis.

作者信息

Kidron Ariel, Nguyen Hiep H, Bayer Jack, Durkin Michael, Harris Daniel, Dang Helen, Diehl Matt, Silver Larry

机构信息

Orthopaedic Surgery, Nova Southeastern University Osteopathic Medicine College of Medicine, Ft. Lauderdale, Florida, USA.

Orthopaedic Surgery, Dr. Kiran C. Patel College of Allopathic Medicine, Ft. Lauderdale, Florida, USA.

出版信息

Orthop Surg. 2022 Jul;14(7):1541-1544. doi: 10.1111/os.13299. Epub 2022 May 19.

DOI:10.1111/os.13299
PMID:35587533
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9251323/
Abstract

Charcot arthropathy is an insidious condition affecting the lower limbs of diabetic patients. It is a complication of diabetic neuropathy resulting from subsequent Wallerian degeneration of the nerves. This complication may eventually lead to limb amputation and a poor patient prognosis if not diagnosed and treated successfully. Herein, we report the case of a 73-year-old female who presented with rapidly progressive bilateral Charcot foot over a 5-week period, necessitating an exostectomy on the mid foot, specifically on the cuboid bone and the navicular cuneiform joint. Her presentation with rapidly progressing foot ulcers on the plantar aspect prompted initial treatment based on osteomyelitis. The report will therefore serve as a useful guide on how to properly treat Charcot foot, which may present in an atypical manner.

摘要

夏科氏关节病是一种隐匿性疾病,影响糖尿病患者的下肢。它是糖尿病神经病变的并发症,由神经随后的沃勒变性引起。如果不能成功诊断和治疗,这种并发症最终可能导致肢体截肢和患者预后不良。在此,我们报告一例73岁女性病例,该患者在5周内出现快速进展的双侧夏科氏足,需要对中足,特别是骰骨和舟楔关节进行外生骨疣切除术。她足底出现快速进展的足部溃疡,促使最初基于骨髓炎进行治疗。因此,本报告将为如何正确治疗可能以非典型方式出现的夏科氏足提供有用的指导。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e437/9251323/cb8d712c13ed/OS-14-1541-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e437/9251323/af64a2942967/OS-14-1541-g001.jpg
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https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e437/9251323/f2db2e9eb525/OS-14-1541-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e437/9251323/a9932b4157e1/OS-14-1541-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e437/9251323/f285cfe65fbe/OS-14-1541-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e437/9251323/cb8d712c13ed/OS-14-1541-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e437/9251323/af64a2942967/OS-14-1541-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e437/9251323/7c4e6668f871/OS-14-1541-g008.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e437/9251323/571f42552cb0/OS-14-1541-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e437/9251323/f2db2e9eb525/OS-14-1541-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e437/9251323/a9932b4157e1/OS-14-1541-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e437/9251323/f285cfe65fbe/OS-14-1541-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e437/9251323/cb8d712c13ed/OS-14-1541-g007.jpg

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本文引用的文献

1
Treatment Failures in Diabetic Foot Osteomyelitis Associated with Concomitant Charcot Arthropathy: The Role of Underlying Arteriopathy.糖尿病足骨髓炎伴发夏科氏关节病治疗失败:潜在动脉病变的作用。
Int J Infect Dis. 2022 Jan;114:15-20. doi: 10.1016/j.ijid.2021.10.036. Epub 2021 Oct 26.
2
Diabetic Wound-Healing Science.糖尿病创面愈合科学。
Medicina (Kaunas). 2021 Oct 8;57(10):1072. doi: 10.3390/medicina57101072.
3
Osteomyelitis Increases the Rate of Amputation in Patients With Type 2 Diabetes and Lower Extremity Burns.
骨髓炎增加了 2 型糖尿病合并下肢烧伤患者的截肢率。
J Burn Care Res. 2020 Sep 23;41(5):981-985. doi: 10.1093/jbcr/iraa106.
4
Effects of immobilization angle on tendon healing after achilles rupture in a rat model.固定角度对大鼠跟腱断裂后愈合的影响。
J Orthop Res. 2019 Mar;37(3):562-573. doi: 10.1002/jor.24241. Epub 2019 Feb 28.
5
Treatment of Charcot Neuroarthropathy and osteomyelitis of the same foot: a retrospective cohort study.同一足部夏科氏神经关节病与骨髓炎的治疗:一项回顾性队列研究。
BMC Musculoskelet Disord. 2017 Nov 16;18(1):460. doi: 10.1186/s12891-017-1818-4.
6
Outcome after protected full weightbearing treatment in an orthopedic device in diabetic neuropathic arthropathy (Charcot arthropathy): a comparison of unilaterally and bilaterally affected patients.糖尿病性神经病变性关节病(夏科氏关节病)采用骨科器械进行保护性完全负重治疗后的结果:单侧和双侧受累患者的比较
BMC Musculoskelet Disord. 2016 Dec 29;17(1):504. doi: 10.1186/s12891-016-1357-4.
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Hemoglobin A1c predicts healing rate in diabetic wounds.糖化血红蛋白可预测糖尿病伤口的愈合速度。
J Invest Dermatol. 2011 Oct;131(10):2121-7. doi: 10.1038/jid.2011.176. Epub 2011 Jun 23.
8
A treatment algorithm for neuropathic (Charcot) midfoot deformity.一种用于神经性(夏科氏)中足畸形的治疗算法。
Foot Ankle. 1993 May;14(4):189-97. doi: 10.1177/107110079301400403.