Anhui Province Key Laboratory of Environment-Friendly Polymer Materials, School of Chemistry & Chemical Engineering, Anhui University, Hefei 230601, China.
Department of Emergency Surgery, the Second Hospital of Anhui Medical University, Hefei, Anhui 230001, China.
J Mater Chem B. 2022 Jun 15;10(23):4405-4415. doi: 10.1039/d2tb00397j.
Molybdenum disulfide (MoS) has been reported to possess photocatalytic bactericidal ability, but its efficiency is not high. In this paper, a water-soluble cationic conjugated polymer, poly(3-(4-methyl-3'-thiophenoxy))propyltrimethylammonium chloride (PThM), was designed to modify MoS and boost its antibacterial abilities. Another hydrophobic conjugated polymer, polythiophene (PTh), was synthesized and composited with MoS, and this was compared with PThM/MoS from the perspective of composite effectiveness. Studies involving the photo-disinfection of () under visible-light irradiation (30 W) showed that the antibacterial efficiencies were in the following order: PThM/MoS > PTh/MoS > MoS. The enhanced bactericidal activities of PThM/MoS and PTh/MoS were attributed to the conjugated polymers restraining the recombination of photogenerated carriers in MoS, thereby increasing the generation of reactive oxygen species (ROS). PThM/MoS presented the best antibacterial efficiency because its cationic side-chains improved the solubility of the material and promoted contact between bacteria and the material. This work may provide some insights into the design of practical nano-antibacterial materials.
二硫化钼（MoS）已被报道具有光催化杀菌能力，但效率不高。本文设计了一种水溶性阳离子共轭聚合物，聚（3-（4-甲基-3'-噻吩氧基）丙基三甲基氯化铵）（PThM），用于修饰 MoS 并提高其抗菌能力。另一种疏水性共轭聚合物聚噻吩（PTh）被合成并与 MoS 复合，并从复合材料有效性的角度与 PThM/MoS 进行了比较。在可见光照射（30 W）下对（）进行光消毒的研究表明，抗菌效率依次为：PThM/MoS > PTh/MoS > MoS。PThM/MoS 和 PTh/MoS 增强的杀菌活性归因于共轭聚合物抑制了 MoS 中光生载流子的复合，从而增加了活性氧物种（ROS）的产生。PThM/MoS 表现出最佳的抗菌效率，因为其阳离子侧链提高了材料的溶解度并促进了细菌与材料的接触。这项工作可能为设计实用的纳米抗菌材料提供一些思路。
