中国社区居住的老年人群中，丧失磨牙与肌肉减少症的相关性。

Association of Loss of Occlusal Pairs of Teeth with Sarcopenia in a Chinese Population of Community-Dwelling Elderly.

机构信息

Wei Gao, MD, PhD, Department of Geriatrics, Sir Run Run Hospital, Nanjing Medical University, 211166, Nanjing, Jiangsu Province, China. Email:

出版信息

J Nutr Health Aging. 2022;26(5):439-444. doi: 10.1007/s12603-022-1784-x.

DOI:10.1007/s12603-022-1784-x

PMID:35587755

Abstract

OBJECTIVES

Tooth loss, which usually leads to malnutrition, is common in the elderly. However, limited information is available regarding its association with sarcopenia. This study aimed to investigate the relationship between loss of occlusal pairs of tooth and sarcopenia.

DESIGN

A cross-sectional retrospective study was performed.

SETTING

The elderly who participated in the National Basic Public Health Project in the Maigaoqiao Community Medical Center in Nanjing, Jiangsu Province, China.

PARTICIPANTS

A total of 2850 individuals aged ≥60 years were enrolled.

MEASUREMENTS

Sarcopenia was defined according to the criteria proposed by the Asian Working Group for Sarcopenia. A trained dentist assessed oral health status and counted the number of present teeth. Logistic regression analyses were performed to evaluate the association between the loss of occlusal pairs and sarcopenia.

RESULTS

The prevalence of sarcopenia was 7.1% (201/2850). Univariate logistic regression analysis showed that loss of occlusal pairs was associated with sarcopenia [anterior occlusal pairs (AOPs): odd ratio (OR) = 1.292, 95% confidence interval (CI) = 1.158-1.442; posterior occlusal pairs (POPs): OR = 1.147, 95% CI = 1.018-1.221]. Multivariate logistic regression analysis indicated that loss of POPs was still an independent risk for sarcopenia (OR = 1.108, 95% CI = 1.007-1.220) after adjustment for traditional confounders. Subgroup analysis showed that loss of POPs was more significantly linked to sarcopenia in those with advanced age (≥80years) (OR = 1.307, 95% CI = 1.116-1.532) and in females (OR = 1.165, 95%CI = 1.038-1.308). Compared to individuals with ≥5 occluding pairs of POPs, those with <5 occluding pairs of POPs had a higher incidence of sarcopenia.

CONCLUSIONS

Loss of POPs is associated with an increased risk of sarcopenia in the elderly in a Chinese population. Further research on the mechanism of the observed causal relationship is needed.

摘要

目的

牙齿缺失通常会导致营养不良，在老年人中很常见。然而，关于其与肌肉减少症的关系的信息有限。本研究旨在探讨缺失的咬合对与肌肉减少症之间的关系。

设计

这是一项横断面回顾性研究。

地点

在中国江苏省南京市迈皋桥社区卫生服务中心参加国家基本公共卫生项目的老年人。

参与者

共纳入 2850 名年龄≥60 岁的个体。

测量方法

根据亚洲肌肉减少症工作组提出的标准定义肌肉减少症。一名经过培训的牙医评估口腔健康状况并计算现有的牙齿数量。进行逻辑回归分析以评估缺失的咬合对与肌肉减少症之间的关联。

结果

肌肉减少症的患病率为 7.1%（201/2850）。单因素逻辑回归分析显示，缺失的咬合对与肌肉减少症有关（前咬合对（AOP）：比值比（OR）=1.292，95%置信区间（CI）=1.158-1.442；后咬合对（POP）：OR=1.147，95%CI=1.018-1.221）。多因素逻辑回归分析表明，调整传统混杂因素后，缺失 POP 仍然是肌肉减少症的独立危险因素（OR=1.108，95%CI=1.007-1.220）。亚组分析表明，缺失 POP 与高龄（≥80 岁）（OR=1.307，95%CI=1.116-1.532）和女性（OR=1.165，95%CI=1.038-1.308）中的肌肉减少症更为显著相关。与具有≥5 个 POP 咬合对的个体相比，具有<5 个 POP 咬合对的个体肌肉减少症的发生率更高。