Jiang Qiuxia, Li Anquan, Liu Xiang, Yu Yue, Zhu Baofu, Cao Hua
School of Chemistry and Chemical Engineering, Guangdong Pharmaceutical University, Zhongshan 528458, P.R. China.
J Org Chem. 2022 Jun 3;87(11):7056-7063. doi: 10.1021/acs.joc.2c00182. Epub 2022 May 19.
An efficient and metal-free approach to the construction of diverse functionalized furan derivatives has been developed from ene-yne-ketones and 1,3,5-triazinanes. As an atom-economical and environment-friendly protocol, the new conditions are suitable for selective C-N and C-O bond formation of a wide range of polysubstituted furans in one pot.
已开发出一种从烯炔酮和1,3,5-三嗪烷构建多种功能化呋喃衍生物的高效无金属方法。作为一种原子经济且环境友好的方案，新条件适用于在一锅反应中选择性地形成多种多取代呋喃的C-N键和C-O键。
