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癌症化疗中预期性恶心的刺激控制

Stimulus control of anticipatory nausea in cancer chemotherapy.

作者信息

Greene P G, Seime R J

出版信息

J Behav Ther Exp Psychiatry. 1987 Mar;18(1):61-4. doi: 10.1016/0005-7916(87)90072-3.

DOI:10.1016/0005-7916(87)90072-3
PMID:3558853
Abstract

A single subject ABA design was used to evaluate the effect of a stimulus manipulation on anticipatory nausea. A lemon solution was orally administered to a 61-year-old female oncology patient in order to mask taste sensations thought to function as a conditioned stimulus eliciting anticipatory symptoms during chemotherapy. A decrease in anticipatory symptoms was observed with the introduction of the taste masking agent and was maintained following withdrawal of the agent.

摘要

采用单一受试者ABA设计来评估刺激操作对预期性恶心的影响。将柠檬溶液口服给予一名61岁的女性肿瘤患者,以掩盖那些被认为在化疗期间作为引发预期症状的条件刺激的味觉感受。随着味觉掩盖剂的引入,预期症状有所减轻,并且在停用该药物后仍保持这种状态。

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D2 Receptors and Sodium Ion Channel Blockades of the Basolateral Amygdala Attenuate Lithium Chloride-Induced Conditioned Taste Aversion Applying to Cancer Chemotherapy Nausea and Vomiting.基底外侧杏仁核的D2受体和钠离子通道阻滞可减轻氯化锂诱导的条件性味觉厌恶,适用于癌症化疗引起的恶心和呕吐。
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