Norton Elizabeth L, Farhat Linda, Wu Xiaoting, Kim Karen M, Fukuhara Shinichi, Patel Himanshu J, Deeb George Michael, Yang Bo
Department of Surgery, Division of Cardiothoracic Surgery, Emory University, Atlanta, Georgia.
Department of Cardiac Surgery, Michigan Medicine, Ann Arbor, Michigan.
Semin Thorac Cardiovasc Surg. 2023;35(3):466-475. doi: 10.1053/j.semtcvs.2022.05.005. Epub 2022 May 16.
With increasing specialization within the field of cardiac surgery and a positive relationship between case volume and surgical outcomes in many areas, the concept of dedicated aortic surgeons performing acute type A aortic dissection (ATAAD) repair was investigated. From 1996 to 2014, 436 patients underwent open surgical repair of an ATAAD and were subsequently divided based on surgeon subspecialization, aortic-surgeon (AS, n = 401) vs non-aortic-surgeon (NAS, n = 35). Each aortic surgeon performed an average of 13 ATAAD repair operations per year. Preoperative comorbidities were similar between groups. Intraoperatively, the AS group had 36% aortic root replacement vs 23% in the NAS group, P = 0.12, and 36% zone 1/2/3 arch replacement vs 26% in the NAS group, P = 0.20). Postoperatively, the AS group had significantly better outcomes, including intraoperative mortality (1.2% vs 5.7%), 30-day mortality (6.5% vs 17%), and composite outcomes (23% vs 46%). Multivariable logistic regression showed NAS was a risk factor for 30-day mortality with an odds ratio (OR) of 4.4 (P = 0.03), as were COPD (OR = 4.0, P = 0.046) and cardiogenic shock (OR = 13.4, P < 0.0001). The 10-year survival was 66% in the AS group vs 46% in the NAS group, P = 0.02. NAS (HR = 2.2), Age (hazard ratio (HR) = 1.05), COPD (HR = 1.96), acute stroke (HR = 3.0), and New York Heart Association class III or IV (HR = 1.75) were significant risk factors for long-term mortality. Managing ATAAD by subspecialized aortic surgeons resulted in improved short- and long-term outcomes. Our specialty could consider ATAAD repair by high-volume aortic surgeons for better patient outcomes.
随着心脏外科领域专业化程度的提高,以及许多领域手术量与手术效果之间存在正相关关系,研究了由专门的主动脉外科医生进行急性A型主动脉夹层(ATAAD)修复的概念。1996年至2014年,436例患者接受了ATAAD的开放手术修复,随后根据外科医生的亚专业进行分组,分为主动脉外科医生组(AS,n = 401)和非主动脉外科医生组(NAS,n = 35)。每位主动脉外科医生每年平均进行13例ATAAD修复手术。两组术前合并症相似。术中,AS组主动脉根部置换率为36%,而NAS组为23%,P = 0.12;1/2/3区主动脉弓置换率AS组为36%,NAS组为26%,P = 0.20。术后,AS组的手术效果明显更好,包括术中死亡率(1.2%对5.7%)、30天死亡率(6.5%对17%)和综合结局(23%对46%)。多变量逻辑回归显示,NAS是30天死亡率的危险因素,比值比(OR)为4.4(P = 0.03),慢性阻塞性肺疾病(COPD,OR = 4.0,P = 0.046)和心源性休克(OR = 13.4,P < 0.0001)也是如此。AS组的10年生存率为66%,NAS组为46%,P = 0.02。NAS(HR = 2.2)、年龄(风险比(HR) = 1.05)、COPD(HR = 1.96)、急性中风(HR = 3.0)以及纽约心脏协会III或IV级(HR = 1.75)是长期死亡率的显著危险因素。由亚专业的主动脉外科医生处理ATAAD可改善短期和长期结局。我们的专业领域可以考虑由高手术量的主动脉外科医生进行ATAAD修复,以获得更好的患者结局。