Amsterdam J D
Int Clin Psychopharmacol. 1986 Jul;1(3):260-2. doi: 10.1097/00004850-198607000-00009.
Loeffler's syndrome (simple pulmonary eosinophilia) is an uncommon side effect of tricyclic antidepressants. It is an allergic reaction characterised by diffuse eosinophilic lung infiltrates and a peripheral blood eosinophilia. It is often asymptomatic, but can also present with mild to moderate pulmonary symptoms. Although it has been only rarely reported with imipramine and desmethylimipramine, it may be a more common side effect to tricyclic antidepressants than has been previously recognized.
吕弗勒综合征（单纯性肺嗜酸性粒细胞增多症）是三环类抗抑郁药罕见的副作用。它是一种过敏反应，其特征为弥漫性嗜酸性粒细胞肺部浸润和外周血嗜酸性粒细胞增多。它通常无症状，但也可能出现轻度至中度肺部症状。尽管仅有少数关于丙咪嗪和去甲丙咪嗪的报道，但它可能是三环类抗抑郁药比之前认识到的更常见的副作用。
