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Ibrutinib attenuated DSS-induced ulcerative colitis, oxidative stress, and the inflammatory cascade by modulating the PI3K/Akt and JNK/NF-κB pathways.

作者信息

Hao Liangliang, Alkry Lina Tariq, Alattar Abdullah, Faheem Muhammad, Alshaman Reem, Shah Fawad Ali, Li Shupeng

机构信息

Hospital of Chengdu University of Traditional Chinese Medicine, China.

College of Natural and Health Sciences, Zayed University, Abu Dhabi, United Arab Emirates.

出版信息

Arch Med Sci. 2022 Apr 20;18(3):805-815. doi: 10.5114/aoms/146792. eCollection 2022.

DOI:10.5114/aoms/146792
PMID:35591835
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9103379/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8bfe/9103379/74e354b633f4/AMS-18-3-146792-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8bfe/9103379/f922921389f2/AMS-18-3-146792-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8bfe/9103379/19f2b3f688a2/AMS-18-3-146792-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8bfe/9103379/478da4bc3665/AMS-18-3-146792-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8bfe/9103379/74e354b633f4/AMS-18-3-146792-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8bfe/9103379/f922921389f2/AMS-18-3-146792-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8bfe/9103379/19f2b3f688a2/AMS-18-3-146792-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8bfe/9103379/478da4bc3665/AMS-18-3-146792-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8bfe/9103379/74e354b633f4/AMS-18-3-146792-g004.jpg

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Carveol a Naturally-Derived Potent and Emerging Nrf2 Activator Protects Against Acetaminophen-Induced Hepatotoxicity.香芹酚是一种天然衍生的强效且新出现的Nrf2激活剂，可预防对乙酰氨基酚诱导的肝毒性。
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Potent Natural Antioxidant Carveol Attenuates MCAO-Stress Induced Oxidative, Neurodegeneration by Regulating the Nrf-2 Pathway.强效天然抗氧化剂香芹酚通过调节Nrf-2途径减轻大脑中动脉闭塞应激诱导的氧化和神经退行性变。
Front Neurosci. 2020 Jun 26;14:659. doi: 10.3389/fnins.2020.00659. eCollection 2020.
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Protective Effects of SIRT6 Overexpression against DSS-Induced Colitis in Mice.
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J Pharm Pharm Sci. 2023 May 25;26:11225. doi: 10.3389/jpps.2023.11225. eCollection 2023.
SIRT6 过表达对 DSS 诱导的小鼠结肠炎的保护作用。
Cells. 2020 Jun 22;9(6):1513. doi: 10.3390/cells9061513.
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Biomed Pharmacother. 2020 Sep;129:110368. doi: 10.1016/j.biopha.2020.110368. Epub 2020 Jun 16.
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