Hadgaonkar Shailesh, Rathi Pradhyumn, Purandare Bharat, Shyam Ashok, Sancheti Parag, Gaikwad Arshaj
Department of Spine, Sancheti Institute of Orthopedics and Rehabilitation, Pune, Maharashtra, India.
Department of Infectious Disease, Sancheti Institute of Orthopedics and Rehabilitation, Pune, Maharashtra, India.
Surg Neurol Int. 2020 Jul 11;11:184. doi: 10.25259/SNI_323_2020. eCollection 2020.
rarely causes spinal infections in patients other than those who are immunocompromised or have sickle cell anemia. Further, most cases occurring in healthy individuals have preexisting gastrointestinal infections. Here, we present a case of pyogenic spondylodiscitis attributed to Typhi, in an immunologically normal patient without gastrointestinal pathology.
A 58-year-old diabetic female complained of lower back pain and malaise. The workup for spinal tuberculosis was negative, but her MRI revealed findings consistent with pyogenic spondylodiscitis (e.g., destruction and instability) for which she required posterior spinal surgery. The organism proved to be . Typhi; she was treated for 2 months and followed-up for 2 years.
spondylodiscitis should be considered among the differential diagnoses for patients with features of infective spondylodiscitis. Culture-specific antibiotics are the cornerstone of treatment, along with appropriate and timely surgery.
除免疫功能低下或患有镰状细胞贫血的患者外，很少引起脊柱感染。此外，大多数发生在健康个体中的病例都有先前存在的胃肠道感染。在此，我们报告一例在无胃肠道病变的免疫正常患者中由伤寒杆菌引起的化脓性脊椎间盘炎病例。
一名58岁的糖尿病女性主诉下背部疼痛和不适。脊柱结核的检查结果为阴性，但她的MRI显示出与化脓性脊椎间盘炎相符的表现（如破坏和不稳定），为此她需要进行后路脊柱手术。病原体被证实为伤寒杆菌；她接受了2个月的治疗，并随访了2年。
对于具有感染性脊椎间盘炎特征的患者，在鉴别诊断中应考虑化脓性脊椎间盘炎。针对特定培养物的抗生素是治疗的基石，同时还需要进行适当且及时的手术。
