Department of Ophthalmology, Balıkesir University Medicine Faculty, Balıkesir, Turkey.
Retina. 2022 Sep 1;42(9):1737-1744. doi: 10.1097/IAE.0000000000003528.
To evaluate the effect of internal limiting membrane (ILM) peeling on anatomical and functional results in pars plana vitrectomy performed eyes with tractional retinal detachment affecting the macula because of diabetes mellitus.
Patients without ILM peeling were considered as Group 1, and patients with ILM peeling were considered as Group 2. The main outcomes were the best-corrected visual acuity at 6 months and the rate of epiretinal membrane formation within 6 months. The rate and the indications for resurgery were determined. Parameters affecting the final best-corrected visual acuity were determined by regression analysis.
Final best-corrected visual acuity was significantly better in eyes with ILM peeled off than in eyes with no peel-off ( P = 0.012). Less secondary epiretinal membrane was formed in Group 1 ( P = 0.009). There was no difference between groups in resurgery rates ( P = 0.143). The need for resurgery because of epiretinal membrane was higher in Group 1 rather than Group 2 ( P = 0.001). The only factor affecting the final best-corrected visual acuity was ILM peeling.
In patients with tractional retinal detachment affecting the macula because of diabetes, ILM peeling in addition to pars plana vitrectomy and membrane excision does not affect the need for resurgery but contributes positively to anatomical and functional outcomes.
评估内界膜(ILM)剥除对因糖尿病引起的牵拉性视网膜脱离影响黄斑的孔源性玻璃体积血患者行标准玻璃体切除术后解剖和功能结果的影响。
未行 ILM 剥除的患者归入第 1 组,而行 ILM 剥除的患者归入第 2 组。主要观察指标为术后 6 个月最佳矫正视力和术后 6 个月内视网膜内膜形成率。确定再次手术的比率和适应证。通过回归分析确定影响最终最佳矫正视力的参数。
与未行 ILM 剥除的患者相比,行 ILM 剥除的患者最终最佳矫正视力显著提高(P=0.012)。第 1 组形成的继发性视网膜内膜较少(P=0.009)。两组再次手术率无差异(P=0.143)。由于视网膜内膜形成而需要再次手术的比率在第 1 组高于第 2 组(P=0.001)。唯一影响最终最佳矫正视力的因素是 ILM 剥除。
对于因糖尿病引起的牵拉性视网膜脱离影响黄斑的患者,在标准玻璃体切除联合膜切除的基础上行 ILM 剥除不会影响再次手术的需要,但对解剖和功能结果有积极影响。