Department of Gastroenterology, The Affiliated Hospital of Northwest University, Xi'an No.3 Hospital, Xi'an, Shaanxi, China.
Emergency Department, Shaanxi Provincial Hospital of Chinese Medicine, Xi'an, Shaanxi, China.
Am J Med Sci. 2022 Oct;364(4):492-498. doi: 10.1016/j.amjms.2022.04.034. Epub 2022 May 17.
Hepatic cortical blindness is an unusual clinical complication of hepatic encephalopathy, and its epidemiology has not been studied in detail. Herein, we present a case report of a 37-year-old male with liver cirrhosis and immunoglobulin A nephropathy who noted visual impairment after eating high-protein food. In addition to the case report, all previously documented cases of hepatic cortical blindness occurring across the globe published from inception until August 2019 were reviewed. The incidence of hepatic cortical blindness is low, and diagnoses are easily missed. The diagnosis of hepatic cortical blindness is dependent on symptoms, and patients may experience several attacks of vision loss. Most patients experience complete blindness, but vision loss recovers within 10 min to one month. Early detection and therapy for hepatic encephalopathy may improve patient outcome.
肝性皮质盲是肝性脑病的一种罕见临床并发症，其流行病学尚未详细研究。在此，我们报告一例 37 岁男性，患有肝硬化和免疫球蛋白 A 肾病，在食用高蛋白食物后出现视力障碍。除了病例报告外，还回顾了截至 2019 年 8 月全球所有已发表的肝性皮质盲病例。肝性皮质盲的发病率较低，且易被误诊。肝性皮质盲的诊断依赖于症状，患者可能会经历几次视力丧失的发作。大多数患者会出现完全失明，但视力丧失会在 10 分钟至一个月内恢复。早期发现和治疗肝性脑病可能会改善患者的预后。
