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KRAS alterations in colorectal liver metastases: shifting to exon, codon, and point mutations.

作者信息

Olthof Pim B, Buettner Stefan, Andreatos Nikolaos, Wang Jane, Løes Inger Marie, Wagner Doris, Sasaki Kazunari, Macher-Beer Andrea, Kamphues Carsten, Pozios Ioannis, Seeliger Hendrik, Morioka Daisuke, Imai Katsunori, Kaczirek Klaus, Pawlik Timothy M, Poultsides George, Burkhart Richard, Endo Itaru, Baba Hideo, Kornprat Peter, Aucejo Federico N, Lønning Per Eystein, Beyer Katharina, Weiss Matthew J, Wolfgang Christopher L, Kreis Martin E, Margonis Georgios A

机构信息

Department of Surgery, Erasmus University, Rotterdam, the Netherlands.

Division of Medical Oncology, Mayo Clinic, Rochester, Minnesota, USA.

出版信息

Br J Surg. 2022 Aug 16;109(9):804-807. doi: 10.1093/bjs/znac147.

DOI:10.1093/bjs/znac147
PMID:35595182
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9380990/
Abstract
摘要

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本文引用的文献

1
KRAS Inhibition with Sotorasib in Advanced Solid Tumors.索托拉西布治疗晚期实体瘤的 KRAS 抑制作用。
N Engl J Med. 2020 Sep 24;383(13):1207-1217. doi: 10.1056/NEJMoa1917239. Epub 2020 Sep 20.
2
Association of RAS Mutation Location and Oncologic Outcomes After Resection of Colorectal Liver Metastases.结直肠癌肝转移切除术后RAS突变位置与肿瘤学结局的相关性
Ann Surg Oncol. 2021 Feb;28(2):817-825. doi: 10.1245/s10434-020-08862-3. Epub 2020 Jul 18.
3
Association of BRAF Mutations With Survival and Recurrence in Surgically Treated Patients With Metastatic Colorectal Liver Cancer.BRAF 突变与手术治疗转移性结直肠癌肝转移患者生存和复发的关系。
JAMA Surg. 2018 Jul 18;153(7):e180996. doi: 10.1001/jamasurg.2018.0996.
4
Mutation location on the RAS oncogene affects pathologic features and survival after resection of colorectal liver metastases.RAS癌基因上的突变位置影响结直肠肝转移瘤切除术后的病理特征和生存情况。
Cancer. 2017 Feb 15;123(4):568-575. doi: 10.1002/cncr.30351. Epub 2016 Oct 13.
5
Prognostic Implication of KRAS Status after Hepatectomy for Colorectal Liver Metastases Varies According to Primary Colorectal Tumor Location.结直肠癌肝转移肝切除术后KRAS状态的预后意义因原发性结直肠癌肿瘤位置而异。
Ann Surg Oncol. 2016 Oct;23(11):3736-3743. doi: 10.1245/s10434-016-5361-6. Epub 2016 Jun 28.
6
Meta-analysis of KRAS mutations and survival after resection of colorectal liver metastases.结直肠癌肝转移切除术后 KRAS 突变与生存的荟萃分析。
Br J Surg. 2015 Sep;102(10):1175-83. doi: 10.1002/bjs.9870. Epub 2015 Jul 21.
7
BRAF codons 594 and 596 mutations identify a new molecular subtype of metastatic colorectal cancer at favorable prognosis.BRAF 密码子 594 和 596 突变鉴定出转移性结直肠癌具有良好预后的新分子亚型。
Ann Oncol. 2015 Oct;26(10):2092-7. doi: 10.1093/annonc/mdv290. Epub 2015 Jul 7.
8
Association Between Specific Mutations in KRAS Codon 12 and Colorectal Liver Metastasis.KRAS基因第12密码子特定突变与结直肠癌肝转移之间的关联
JAMA Surg. 2015 Aug;150(8):722-9. doi: 10.1001/jamasurg.2015.0313.
9
RAS mutation status predicts survival and patterns of recurrence in patients undergoing hepatectomy for colorectal liver metastases.RAS 基因突变状态可预测行肝切除术的结直肠癌肝转移患者的生存和复发模式。
Ann Surg. 2013 Oct;258(4):619-26; discussion 626-7. doi: 10.1097/SLA.0b013e3182a5025a.
10
Specific mutations in KRAS codons 12 and 13, and patient prognosis in 1075 BRAF wild-type colorectal cancers.KRAS 密码子 12 和 13 中的特定突变与 1075 例 BRAF 野生型结直肠癌患者的预后。
Clin Cancer Res. 2012 Sep 1;18(17):4753-63. doi: 10.1158/1078-0432.CCR-11-3210. Epub 2012 Jul 2.