用于克罗恩病诊断和管理的工具。

Tools for the Diagnosis and Management of Crohn's Disease.

机构信息

Division of Gastroenterology, Inflammatory Bowel Diseases Center, Washington University School of Medicine, 600 South Euclid Avenue, Campus Box 8124, Saint Louis, MO 63110, USA.

出版信息

Gastroenterol Clin North Am. 2022 Jun;51(2):213-239. doi: 10.1016/j.gtc.2021.12.003. Epub 2022 Apr 22.

DOI:10.1016/j.gtc.2021.12.003

PMID:35595412

Abstract

Numerous tools have emerged over recent decades to aid in the increasingly complex management of patients with Crohn's disease (CD) beyond endoscopy, including video capsule endoscopy, magnetic resonance enterography, computed tomography enterography, a variety of biomarkers, and even wearable biosensors and smartphone applications. These tools have allowed for a more sophisticated and less invasive complementary approach to the evaluation of disease activity and treatment response in patients with CD. This article details the characteristics, practical application, and limitations of these various modalities and discusses how updated guidelines are now incorporating many of them into a treat-to-target strategy.

摘要

近几十年来，出现了许多工具来帮助管理克罗恩病（CD）患者，这些工具不仅限于内镜，还包括视频胶囊内镜、磁共振肠造影术、计算机断层肠造影术、各种生物标志物，甚至可穿戴生物传感器和智能手机应用程序。这些工具使得对 CD 患者的疾病活动和治疗反应进行更复杂和非侵入性的补充评估成为可能。本文详细介绍了这些不同方式的特点、实际应用和局限性，并讨论了更新的指南如何将其中许多方法纳入靶向治疗策略。