Li Shentong, He Xin, Li Quanlong, Shi Pengfei, Zhang Wangqing
Key Laboratory of Functional Polymer Materials of the Ministry of Education, Collaborative Innovation Center of Chemical Science and Engineering (Tianjin), Institute of Polymer Chemistry, Nankai University, Tianjin 300071, China.
ACS Macro Lett. 2014 Sep 16;3(9):916-921. doi: 10.1021/mz500466x. Epub 2014 Sep 3.
A new and efficient strategy to synthesize multicompartment block copolymer nanoparticles (MCBNs) by two macro-RAFT agents comediated dispersion polymerization is proposed. By simultaneously employing two macro-RAFT agents in dispersion RAFT polymerization, one-pot synthesis of well-defined MCBNs constructed with two diblock copolymers of poly(-butyl methyl acrylate)--polystyrene (PBMA--PS) and poly[-(4-vinylbenzyl)-,-diethylamine]--polystyrene (PVEA--PS) is achieved. These MCBNs contain a PS core and discrete PVEA and/or PBMA nodules on the PS core. By changing the ratio of the two macro-RAFT agents or the polymerization degree of the solvophobic block in the two diblock copolymer mixture, the structure of MCBNs can be tuned. Our strategy overcomes the inconvenience and difficulty in synthesis of MCBNs, and it introduces a valid way to prepare well-defined MCBNs constructed with two or more diblock copolymers.
提出了一种通过两种大分子RAFT试剂共介导的分散聚合来合成多隔室嵌段共聚物纳米粒子（MCBNs）的新型高效策略。通过在分散RAFT聚合中同时使用两种大分子RAFT试剂，实现了一锅法合成由聚（丙烯酸丁酯-甲基丙烯酸甲酯）-聚苯乙烯（PBMA-PS）和聚[ -（4-乙烯基苄基）-，-二乙胺]-聚苯乙烯（PVEA-PS）两种二嵌段共聚物构建的结构明确的MCBNs。这些MCBNs包含一个PS核以及在PS核上离散的PVEA和/或PBMA结节。通过改变两种大分子RAFT试剂的比例或两种二嵌段共聚物混合物中疏溶剂嵌段的聚合度，可以调节MCBNs的结构。我们的策略克服了MCBNs合成中的不便和困难，并引入了一种制备由两种或更多种二嵌段共聚物构建的结构明确的MCBNs的有效方法。
