Utama Robert H, Drechsler Markus, Förster Stephan, Zetterlund Per B, Stenzel Martina H
Centre for Advanced Macromolecular Design (CAMD), School of Chemical Engineering, and ∥Centre for Advanced Macromolecular Design (CAMD), School of Chemistry, University of New South Wales, Sydney, Australia.
Bayreuth Institute of Macromolecular Research (BIMF) and §Physikalische Chemie I, Universität Bayreuth, Bayreuth, Germany.
ACS Macro Lett. 2014 Sep 16;3(9):935-939. doi: 10.1021/mz5005019. Epub 2014 Sep 4.
We report herein the versatility of inverse miniemulsion periphery RAFT polymerization (IMEPP) and postpolymerization reaction in producing pH-responsive nanocapsules with different functionalities. The robustness of the polymeric nanocapsules was confirmed by their ability to undergo reactions, be dried, and be redispersed in various solvents without any changes in size and core-shell morphology. Nanocapsules bearing carboxylic acid (COOH) functionalities were produced via hydrolysis, while nanocapsules bearing tertiary-amine (N-X) functionalities were synthesized via aminolysis. The responsive behavior of the nanocapsules was tested in aqueous solution with pHs ranging from 3 to 12. Nanocapsules with COOH functionalities were found to swell under basic conditions due to the deprotonated carboxylate ions. In contrast, nanocapsule with tertiary amine functionalities underwent swelling in acidic conditions.
我们在此报告了反向微乳液周边可逆加成-断裂链转移聚合（IMEPP）和聚合后反应在制备具有不同功能的pH响应纳米胶囊方面的多功能性。聚合物纳米胶囊的稳健性通过其进行反应、干燥并重新分散在各种溶剂中而尺寸和核壳形态无任何变化的能力得到证实。带有羧酸（COOH）功能的纳米胶囊通过水解制备，而带有叔胺（N-X）功能的纳米胶囊通过氨解合成。在pH值范围为3至12的水溶液中测试了纳米胶囊的响应行为。发现具有COOH功能的纳米胶囊在碱性条件下由于去质子化的羧酸根离子而膨胀。相反，具有叔胺功能的纳米胶囊在酸性条件下膨胀。
