Lipton R B, Berger A R, Lesser M L, Lantos G, Portenoy R K
J Neurol. 1987 Feb;234(2):86-90. doi: 10.1007/BF00314107.
One hundred and twelve patients with spontaneous supratentorial intracerebral hemorrhages were reviewed to identify features which distinguish lobar intracerebral hemorrhage (LH; n = 42) from thalamic or basal ganglionic hemorrhage (TGH; n = 70). Chronic hypertension occurred more commonly in TGH (TGH 67%; LH 48%) while bleeding diathesis was more common in LH (LH 19%; TGH 6%). Clinical presentations were extremely variable and not associated with the type of hemorrhage. Bleeding into the ventricles and hydrocephalus occurred more often with TGH. At last follow-up, there were minimal differences between LH and TGH in overall mortality and functional outcome of the survivors. Alertness on admission was associated with a good outcome regardless of the type of hemorrhage, while a low Glasgow Coma Scale score, coma, ataxic respiration, abnormal pupil reactions, acute hypertension, large hemorrhage size and intraventricular blood were associated with a poor outcome. These data confirm etiological distinctions between LH and TGH, but fail to confirm previously reported differences in clinical presentation and outcome.
对112例自发性幕上脑出血患者进行了回顾性研究,以确定区分脑叶脑出血(LH;n = 42)与丘脑或基底节区脑出血(TGH;n = 70)的特征。慢性高血压在TGH中更为常见(TGH为67%;LH为48%),而出血素质在LH中更为常见(LH为19%;TGH为6%)。临床表现差异极大,且与出血类型无关。TGH患者脑室出血和脑积水更为常见。在最后一次随访时,LH和TGH在总体死亡率和幸存者功能结局方面差异极小。无论出血类型如何,入院时意识清醒与良好结局相关,而格拉斯哥昏迷量表评分低、昏迷、共济失调呼吸、瞳孔反应异常、急性高血压、出血量大和脑室内出血与不良结局相关。这些数据证实了LH和TGH之间的病因学差异,但未能证实先前报道的临床表现和结局差异。