Willshaw H E, Deady J P
J Pediatr Surg. 1987 Mar;22(3):281-3. doi: 10.1016/s0022-3468(87)80348-2.
Vascular hamartomas in childhood may occur in isolation, or in a more generalized form with both cutaneous and visceral involvement. Many isolated hamartomas require no active intervention, but those arising around the eye may seriously compromise developing vision, either by obscuring the visual axis, or by modifying the refractive status of the involved eye. Therefore, lesions in this site demand vigorous treatment if sight-threatening complications are to be avoided. We report our experience in treating 15 children using local steroid injections to accelerate regression of such vascular hamartomas. Seven of the children (46.7%) showed complete regression of their hemangiomas, and only two (13.3%) showed no response to the injections. Intralesional steroid injection seems to be a relatively effective, safe, and nondisfiguring method of dealing with periocular vascular malformations.
儿童期的血管性错构瘤可能单独出现,也可能以更广泛的形式出现,累及皮肤和内脏。许多孤立的错构瘤无需积极干预,但眼部周围出现的错构瘤可能会严重损害视力发育,要么遮挡视轴,要么改变患眼的屈光状态。因此,如果要避免视力威胁性并发症,该部位的病变需要积极治疗。我们报告了使用局部类固醇注射治疗15名儿童此类血管性错构瘤以加速其消退的经验。7名儿童(46.7%)的血管瘤完全消退,只有2名儿童(13.3%)对注射无反应。瘤内类固醇注射似乎是一种相对有效、安全且不留瘢痕的处理眼周血管畸形的方法。