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Solute transport resistance at water-oil interfaces.

作者信息

Leahy D E, Wait A R

出版信息

J Pharm Sci. 1986 Dec;75(12):1157-61. doi: 10.1002/jps.2600751208.

DOI:10.1002/jps.2600751208
PMID:3559925
Abstract

The barriers to transport of methyl nicotinate across the water-octanol, water-2,2,4-trimethylpentane, and water-isopropyl myristate interfaces at 25 degrees C have been studied using a rotating diffusion cell. Comparison of results for systems which comprise zero, one, and two interfacial barriers shows that, contrary to previous reports, interfacial resistance is not a significant barrier in these cases and is below the limit of detection of the rotating diffusion cell method.

摘要

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