Zhang X, Bao H D, Shu S B, Liu Z, Qiu Y, Zhu Z Z
Division of Spine Surgery, Department of Orthopedic Surgery, Nanjing Drum Tower Hospital, the Affiliated Hospital of Nanjing University Medical School, Nanjing 210008, China.
Zhonghua Yi Xue Za Zhi. 2022 May 24;102(19):1458-1463. doi: 10.3760/cma.j.cn112137-20211221-02841.
To analyze the relationship between post-operative proximal junctional kyphosis (PJK) and C-femoral heads center (C-FH), pelvic fixation in adult spinal deformity (ASD) patients, so as to provide a reference for the preoperative decision-making and the postoperative intervention timely. It was a retrospective study that analyzed 34 cases of ASD patients who underwent posterior pedicle screw fixation in Nanjing Drum Tower Hospital between January 2017 and May 2017. ASD patients were divided into two groups according to fixation options: the sacroiliac fixation group and the non-sacroiliac fixation group. The spine-pelvis parameters were evaluated on full-length X ray films of spine at preoperatively, 2 weeks postoperatively and the last follow-up, and the incidence of PJK was recorded. A total of 34 ASD patients (3 males and 31 females) were included in this study, with an average age of (58±6) years. The mean follow-up period was (2.9±1.0) years (2.0-4.0 years). The age, follow-up time and various spine-pelvis parameters showed no significant differences between the two groups (all >0.05). The immediate postoperative C-FH in the sacroiliac fixation group was significantly lower than that in the non-sacroiliac fixation group [(-69.46±30.85) mm vs (-31.62±15.31) mm, <0.001]. The incidence of PJK was as high as 50.0% (8/16) in patients with sacroiliac fixation, but it was only 22% (4/18) in patients without sacroiliac fixation (=0.016). At the last follow-up, the C-FH of both groups were both higher than -20 mm (both were approximately -15 mm, =0.976), indicating that the C-FH was compensated in both groups. Due to the loss of the distal compensation ability, the incidence of PJK in the sacroiliac fixation group was higher than that in the non-sacroiliac fixation group. Due to the fixation of pelvis and most of lumbar spine, no significant differences were found in lumbar lordosis (LL), pelvic tilt (PT) and sacral slope (SS) at the last follow-up in both groups when compared with those after the operation (all >0.05); while the thoracic kyphosis (TK) and cervical lordosis (CL) increased significantly (both <0.05) to compensate C-FH at the last follow-up. It's demonstrated that C-FH< -2 cm and pelvic fixation are high risk factors of PJK in ASD patients. It is suggested that both global sagittal balance and pelvic fixation should be considered in decision-making and corrective surgery, rather than only focusing on spine-pelvic parameters.
分析成人脊柱畸形(ASD)患者术后近端交界性后凸(PJK)与C型股骨头中心(C-FH)、骨盆固定之间的关系,为术前决策及术后及时干预提供参考。本研究为回顾性研究,分析了2017年1月至2017年5月在南京鼓楼医院接受后路椎弓根螺钉固定的34例ASD患者。根据固定方式将ASD患者分为两组:骶髂固定组和非骶髂固定组。在术前、术后2周及末次随访时,通过脊柱全长X线片评估脊柱-骨盆参数,并记录PJK的发生率。本研究共纳入34例ASD患者(男3例,女31例),平均年龄(58±6)岁。平均随访时间为(2.9±1.0)年(2.0 - 4.0年)。两组患者的年龄、随访时间及各项脊柱-骨盆参数比较,差异均无统计学意义(均>0.05)。骶髂固定组术后即刻C-FH显著低于非骶髂固定组[(-69.46±30.85)mm vs(-31.62±15.31)mm,<0.001]。骶髂固定患者PJK发生率高达50.0%(8/16),而非骶髂固定患者仅为22%(4/18)(=0.016)。末次随访时,两组C-FH均高于-20 mm(均约为-15 mm,=0.976),表明两组C-FH均得到代偿。由于远端代偿能力丧失,骶髂固定组PJK发生率高于非骶髂固定组。由于骨盆及大部分腰椎得到固定,两组末次随访时腰椎前凸(LL)、骨盆倾斜(PT)和骶骨斜率(SS)与术后相比,差异均无统计学意义(均>0.05);而末次随访时胸椎后凸(TK)和颈椎前凸(CL)显著增加(均<0.05)以代偿C-FH。结果表明,C-FH < -2 cm及骨盆固定是ASD患者发生PJK的高危因素。建议在决策及矫正手术时,应综合考虑整体矢状面平衡及骨盆固定,而非仅关注脊柱-骨盆参数。