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角膜穿孔中氰基丙烯酸酯胶水贴片的光学相干断层扫描结果

Optical coherence tomography findings of cyanoacrylate glue patch in corneal perforations.

作者信息

Polania-Baron Eduardo J, Gonzalez-Lubcke Eduardo, Graue-Hernandez Enrique O, Ramirez-Miranda Arturo, Navas Alejandro

机构信息

Department of Cornea, External Diseases and Refractive Surgery, Institute of Ophthalmology "Conde de Valenciana", Mexico City, Mexico.

出版信息

Am J Ophthalmol Case Rep. 2022 May 13;27:101576. doi: 10.1016/j.ajoc.2022.101576. eCollection 2022 Sep.

DOI:10.1016/j.ajoc.2022.101576
PMID:35599953
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9121234/
Abstract

PURPOSE

To report a cases series of corneal perforations treated with cyanoacrylate glue patch (CGP) assessed with optical coherence tomography for monitoring corneal status in long-term follow-up examinations.

OBSERVATIONS

CPG was successfully used as primary treatment in three cases of corneal perforations. Spontaneous loosening or dislodging of the CPG did not occur in the follow-up. Anterior segment optical coherence tomography (AS-OCT) was performed to monitor wound healing at the site of perforation before considering the CGP removal. The presence of normal epithelium layer beneath the glue patch and stromal regeneration tissue were confirmed by AS-OCT, and glue patch was safely removed.

CONCLUSIONS AND IMPORTANCE

The area of healing tissue beneath the CGP may not be easy to evaluate using the slit-lamp microscopy alone. AS-OCT is a useful tool in the assessment of corneal healing tissue in the presence of cyanoacrylate glue patch.

摘要

目的

报告一系列使用氰基丙烯酸酯胶水贴片(CGP)治疗角膜穿孔的病例,并通过光学相干断层扫描评估其在长期随访检查中对角膜状态的监测情况。

观察结果

CGP成功用于3例角膜穿孔的初始治疗。随访期间未发生CGP自发松动或移位。在考虑移除CGP之前,进行眼前节光学相干断层扫描(AS-OCT)以监测穿孔部位的伤口愈合情况。AS-OCT证实胶水贴片下方存在正常上皮层和基质再生组织,且胶水贴片被安全移除。

结论与意义

仅使用裂隙灯显微镜可能不易评估CGP下方愈合组织的面积。AS-OCT是评估存在氰基丙烯酸酯胶水贴片时角膜愈合组织的有用工具。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8e1f/9121234/0d5b53c83749/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8e1f/9121234/d445a804c3a5/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8e1f/9121234/0d5b53c83749/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8e1f/9121234/d445a804c3a5/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8e1f/9121234/0d5b53c83749/gr2.jpg

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本文引用的文献

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Efficacy of cyanoacrylate tissue adhesive in the management of corneal thinning and perforation due to microbial keratitis.氰基丙烯酸酯组织粘合剂在治疗微生物性角膜炎导致的角膜变薄和穿孔中的疗效。
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Br J Ophthalmol. 2020 Sep;104(9):1304-1309. doi: 10.1136/bjophthalmol-2019-315098. Epub 2019 Dec 10.
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Anterior segment optical coherence tomography.眼前节光学相干断层扫描。
Prog Retin Eye Res. 2018 Sep;66:132-156. doi: 10.1016/j.preteyeres.2018.04.002. Epub 2018 Apr 7.
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Anterior segment optical coherence tomography for the diagnosis of corneal dystrophies according to the IC3D classification.根据 IC3D 分类的角膜营养不良的前节光学相干断层扫描诊断。
Surv Ophthalmol. 2018 May-Jun;63(3):365-380. doi: 10.1016/j.survophthal.2017.08.001. Epub 2017 Aug 9.
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Wound healing process after corneal stromal thinning observed with anterior segment optical coherence tomography.眼前节光学相干断层扫描观察角膜基质变薄后的伤口愈合过程。
Cornea. 2014 Oct;33(10):1056-60. doi: 10.1097/ICO.0000000000000223.
8
Management of nontraumatic corneal perforation with tectonic drape patch and cyanoacrylate glue.应用组织补片和氰基丙烯酸酯胶治疗非外伤性角膜穿孔。
Cornea. 2010 Oct;29(10):1173-5. doi: 10.1097/ICO.0b013e3181d5d996.
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Assessment of the use of anterior segment optical coherence tomography in microbial keratitis.眼前节光学相干断层扫描在微生物性角膜炎中的应用评估
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The effectiveness of isobutyl cyanoacrylate tissue adhesive for the treatment of corneal perforations.氰基丙烯酸异丁酯组织黏合剂治疗角膜穿孔的有效性。
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