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以原发性不孕和CA-125持续升高为表现的女性生殖器结核:一例报告

Female genital tuberculosis presented with primary infertility and persistent CA-125 elevation: A case report.

作者信息

Feng Qian, Hu Xiaoxia, Zhao Jing, Huang Jingyao, Liu Liling

机构信息

Department of Obstetrics and Gynaecology, Monash University, Melbourne, 3800, Australia.

Guangxi Academy of Medical Sciences & Department of Gynaecology, The People's Hospital of Guangxi Zhuang Autonomous Region, 530000, Nanning, China.

出版信息

Ann Med Surg (Lond). 2022 May 3;78:103683. doi: 10.1016/j.amsu.2022.103683. eCollection 2022 Jun.

Abstract

INTRODUCTION

and importance: Tuberculosis is one of the leading causes of mortality in many developing countries. Female genital tuberculosis, a relatively uncommon form of tuberculosis, is critically challenging to diagnose due to its insidious and non-typical presentations.

CASE PRESENTATION

Herein, we present with an asymptomatic infertile woman with persistently high CA-125 passed undiagnosed until laparoscopy unveiled the diagnosis of TB.

CLINICAL DISCUSSION

In this study, we highlight the diagnostic complexities in female genital tuberculosis and demonstrate the value of the CA-125 increase in prompting the suspicion of tuberculosis in the appropriate clinical context.

CONCLUSION

Given the considerably large number of individuals with tuberculosis in China, we strongly recommend routine tuberculosis screening in women seeking infertility care in China.

摘要

引言

及重要性:结核病是许多发展中国家的主要死因之一。女性生殖器结核是一种相对不常见的结核病形式,因其隐匿性和非典型表现,诊断极具挑战性。

病例报告

在此,我们报告一名无症状的不孕女性,其CA - 125持续升高,一直未被诊断出来,直到腹腔镜检查才揭示出结核病的诊断。

临床讨论

在本研究中,我们强调了女性生殖器结核的诊断复杂性,并证明了在适当的临床背景下,CA - 125升高对提示结核病怀疑的价值。

结论

鉴于中国结核病患者数量众多,我们强烈建议在中国寻求不孕治疗的女性中进行常规结核病筛查。

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本文引用的文献

1
CA 125 and TB.CA 125 和结核。
BMJ Case Rep. 2021 Jan 18;14(1):e238199. doi: 10.1136/bcr-2020-238199.
3
Genital tuberculosis screening at an academic fertility center in the United States.美国一学术生育中心的生殖器结核筛查。
Am J Obstet Gynecol. 2020 Nov;223(5):737.e1-737.e10. doi: 10.1016/j.ajog.2020.05.045. Epub 2020 Jun 1.
8
Usefulness of CA125 in the differential diagnosis of uterine adenomyosis and myoma.CA125在子宫腺肌病与子宫肌瘤鉴别诊断中的应用价值
Eur J Obstet Gynecol Reprod Biol. 2015 Feb;185:131-5. doi: 10.1016/j.ejogrb.2014.12.008. Epub 2014 Dec 16.
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The clinical significance of CA-125 in pulmonary tuberculosis.CA-125 在肺结核中的临床意义。
Tuberculosis (Edinb). 2013 Mar;93(2):222-6. doi: 10.1016/j.tube.2012.10.014. Epub 2013 Feb 12.

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