Kahl L, Medsger T A
J Rheumatol. 1986 Dec;13(6):1063-5.
A clinical syndrome consisting of severe acute nocturnal knee arthralgias, absent signs of inflammation, and spontaneous resolution in 12 to 72 h was observed in 3 patients in close temporal relationship to wide swings in corticosteroid dosage. A similar clinical picture has previously been described in several renal transplant recipients. With increasing use of pulse corticosteroid treatment for a variety of medical and surgical conditions, this disorder is likely to be encountered in many different settings and deserves recognition because of its dramatic presentation and self-limited course.
在3例患者中观察到一种临床综合征，其特征为严重的急性夜间膝关节疼痛、无炎症体征且在12至72小时内自发缓解，这些患者的症状与皮质类固醇剂量的大幅波动在时间上密切相关。此前在几名肾移植受者中也曾描述过类似的临床表现。随着脉冲皮质类固醇治疗在各种内科和外科疾病中的应用日益增加，这种疾病可能会在许多不同情况下出现，因其表现显著且病程自限，值得引起重视。
