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膀胱炎性肌纤维母细胞瘤:一例报告并文献复习

Inflammatory myofibroblastic tumour of the bladder: a case report and review of the literature.

作者信息

Marais Bernard, Eyal Paula, Kesner Ken, John Jeff

机构信息

Division of Urology, Department of Surgery, Frere Hospital and Walter Sisulu University, East London 5200, South Africa.

Pathcare Laboratories, George, South Africa.

出版信息

Ther Adv Urol. 2022 May 17;14:17562872221096385. doi: 10.1177/17562872221096385. eCollection 2022 Jan-Dec.

Abstract

Inflammatory myofibroblastic tumours (IMTs) are rare neoplasms of uncertain malignant potential that closely resemble other more aggressive spindle cell tumours. The distinction of IMT from the latter is of importance. We report a case of IMT in a 27-year-old man who presented with intermittent painless, macroscopic haematuria and was found to have a large bladder mass arising from the dome of the bladder. The tumour was resected transurethrally, and histology and immunohistochemistry were consistent with an IMT of the bladder. Our patient remained asymptomatic at follow-up 3 months later, when cystoscopy noted no regrowth of the residual tumour. Transurethral resection resection of bladder tumour, partial cystectomy and radical cystectomy form the mainstay of treatment of IMT. However, the optimal management of this condition remains uncertain due to the sparsity of reported cases.

摘要

炎性肌纤维母细胞瘤(IMTs)是一种恶性潜能不确定的罕见肿瘤,与其他更具侵袭性的梭形细胞肿瘤极为相似。将IMT与后者区分开来很重要。我们报告了一例27岁男性的IMT病例,该患者表现为间歇性无痛肉眼血尿,经检查发现膀胱顶部有一个巨大的膀胱肿块。肿瘤经尿道切除,组织学和免疫组化结果与膀胱IMT相符。3个月后随访时,我们的患者无症状,膀胱镜检查未发现残留肿瘤复发。经尿道膀胱肿瘤切除术、膀胱部分切除术和根治性膀胱切除术是IMT的主要治疗方法。然而,由于报道的病例较少,这种疾病的最佳治疗方案仍不确定。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a756/9118416/5232c88bd74c/10.1177_17562872221096385-fig1.jpg

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