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年轻女性膀胱炎性肌纤维母细胞瘤:一例关于诊断与治疗挑战的病例报告

Inflammatory Myofibroblastic Tumor of the Urinary Bladder of a Young Female: A Case Report on Diagnosis and Management Challenges.

作者信息

Almutairi Sulaiman

机构信息

Department of Urology, College of Medicine, Majmaah University, Al-Majmaah, Saudi Arabia.

出版信息

J Pharm Bioallied Sci. 2024 Jul;16(Suppl 3):S2987-S2990. doi: 10.4103/jpbs.jpbs_224_24. Epub 2024 May 24.

Abstract

Inflammatory myofibroblastic tumor (IMT) is a rare tumor with intermediate biologic potential, in which lack of understanding often poses difficulties in preoperative diagnosis and management. We report a case in which a 25-year-old female patient not known to have any medical illness presented with gross hematuria for one month. The patient was investigated with urine analysis, urine culture, urine cytology, and Ct-Urogram at a urology clinic. Her investigation showed a urinary bladder dome enhancing mass 3.6 * 3.8 * 3.3 cm with minimal surrounding perivesical stranding worrisome for early peritoneal carcinomatosis. She underwent cystoscopy and transurethral bladder tumor resection; resection was not complete due to the size of bladder mass. Six units of packed red blood cells were given. Histopathology showed IMT. Case was discussed in the tumor board and the patient underwent laparoscopic urachal resection and partial cystectomy. Discharged on day three post-op with Foley catheter and appointment for cystogram after 2 weeks. Histopathology confirms the diagnosis of IMT with four millimeters of free margin and two benign regional reactive lymph nodes. Patients were followed for two years with no sign of recurrence or any lower urinary tract symptoms. Our report reinforces the standard diagnostic and management approach, supporting consistent findings and successful surgical strategies, to enhance patient care and understanding of this rare neoplasm.

摘要

炎性肌纤维母细胞瘤(IMT)是一种具有中等生物学潜能的罕见肿瘤,对其认识不足常常给术前诊断和治疗带来困难。我们报告一例病例,一名25岁无任何病史的女性患者出现肉眼血尿1个月。该患者在泌尿外科门诊接受了尿液分析、尿培养、尿细胞学检查和CT尿路造影检查。检查显示膀胱顶部有一强化肿块,大小为3.6×3.8×3.3 cm,周围膀胱周围仅有轻微条索状影,令人担心早期腹膜癌转移。她接受了膀胱镜检查和经尿道膀胱肿瘤切除术;由于膀胱肿块较大,切除不完全。输注了6单位浓缩红细胞。组织病理学显示为IMT。该病例在肿瘤讨论会上进行了讨论,患者随后接受了腹腔镜脐尿管切除术和部分膀胱切除术。术后第3天带导尿管出院,2周后预约膀胱造影检查。组织病理学确诊为IMT,切缘有4毫米,有两个良性区域反应性淋巴结。对患者进行了两年的随访,未发现复发迹象或任何下尿路症状。我们的报告强化了标准的诊断和治疗方法,支持一致的发现和成功的手术策略,以加强对该罕见肿瘤的患者护理和认识。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7d75/11426765/69a11ecf8e41/JPBS-16-2987-g001.jpg

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