Orellana Taylor, Ross Malcolm, Dressen Michael, Beriwal Sushil, Berger Jessica L
Division of Gynecologic Oncology, Department of Obstetrics, Gynecology, and Reproductive Sciences, Magee-Womens' Hospital of UPMC, 300 Halket Street, Pittsburgh, PA 15213, USA.
Department of Radiology, University of Pittsburgh, Pittsburgh, PA, USA.
Radiol Case Rep. 2022 May 17;17(7):2554-2558. doi: 10.1016/j.radcr.2022.04.035. eCollection 2022 Jul.
Metastatic patterns of squamous cell cervical cancer are well described in the literature. Advancements in radiologic imaging have improved the ability to detect unusual sites of metastatic disease. We describe a unique case of isolated distant metastases to the skeletal muscle and adipose tissue detected by PET-CT. A patient with a new diagnosis of squamous cell cervical cancer was incidentally found to have FDG-avid lesions in the right upper extremity skeletal muscle and right gluteal adipose tissue without other evidence of metastatic disease. Initial cytology of the right upper extremity lesion revealed no evidence of malignancy. After the patient developed worsening pain and swelling in the right arm and gluteal region, repeat cytology confirmed metastatic squamous cell cervical cancer. With increasing sensitivity of radiologic imaging studies, the frequency of incidentally noted lesions is likely to rise and may be challenging to interpret in a patient with a history of malignancy. Continued assessment and reporting of these lesions is imperative for improved understanding of the natural history of disease.
宫颈癌鳞状细胞的转移模式在文献中有详尽描述。放射影像学的进展提高了检测转移性疾病不寻常部位的能力。我们描述了一例通过PET-CT检测到的孤立性远处转移至骨骼肌和脂肪组织的独特病例。一名新诊断为宫颈癌鳞状细胞的患者偶然发现右上肢骨骼肌和右臀脂肪组织有FDG摄取增加的病变，而无其他转移性疾病证据。右上肢病变的初始细胞学检查未发现恶性证据。在患者右上肢和臀部区域疼痛和肿胀加重后，重复细胞学检查确诊为转移性宫颈癌鳞状细胞。随着放射影像学研究敏感性的提高，偶然发现的病变频率可能会上升，对于有恶性肿瘤病史的患者来说，对这些病变的解读可能具有挑战性。持续评估和报告这些病变对于更好地了解疾病的自然史至关重要。
