Department of Radiology, The Third Affiliated Hospital of Jinzhou Medical University, Jinzhou 121000, Liaoning, China.
Department of Radiology, The Third Affiliated Hospital of Chongqing Medical University, Chongqing 401120, China.
Contrast Media Mol Imaging. 2022 May 6;2022:5459779. doi: 10.1155/2022/5459779. eCollection 2022.
To summarize the value of multislice spiral CT (MSCT) in the differential diagnosis of thick-wall gallbladder carcinoma (TWGC) and chronic cholecystitis (CC), the clinical data of 36 patients with TWGC and 60 patients with chronic cholecystitis who were treated in our hospital from January 2017 to May 2021 were retrospectively analyzed, and the CT image features and diagnostic accuracy of the patients were summarized. Compared with the CC group, the proportions of disruption of gallbladder mucosa line, blurred gallbladder outline, high obstruction of biliary tract, lymphomegaly, adjacent invasion, peritoneal effusion, wall nodules, and the gallbladder wall thickness in the TWGC group were higher, with statistical significance ( < 0.05). Thirty-four patients with TWGC and 62 patients with chronic cholecystitis were diagnosed by MSCT. The sensitivity and specificity of MSCT in diagnosing TWGC were 86.11% and 95.00%, respectively. The positive likelihood ratio was 17.222 and the negative likelihood ratio was 0.1462. The positive prediction rate was 91.18%, the negative prediction rate was 91.94%, and the correct rate was 91.67%. MSCT can show the characteristic difference between TWGC and chronic cholecystitis, which can be used for differential diagnosis.
为了总结多层螺旋 CT（MSCT）在鉴别诊断厚壁胆囊癌（TWGC）和慢性胆囊炎（CC）中的价值，回顾性分析了 2017 年 1 月至 2021 年 5 月在我院治疗的 36 例 TWGC 患者和 60 例慢性胆囊炎患者的临床资料，总结了患者的 CT 图像特征和诊断准确性。与 CC 组相比，TWGC 组的胆囊黏膜线中断、胆囊轮廓模糊、胆道高位梗阻、淋巴结肿大、邻近侵犯、腹腔积液、壁结节和胆囊壁增厚的比例较高，差异有统计学意义（<0.05）。34 例 TWGC 患者和 62 例慢性胆囊炎患者经 MSCT 诊断，MSCT 诊断 TWGC 的灵敏度和特异度分别为 86.11%和 95.00%，阳性似然比为 17.222，阴性似然比为 0.1462，阳性预测率为 91.18%，阴性预测率为 91.94%，准确率为 91.67%。MSCT 能显示 TWGC 和慢性胆囊炎之间的特征性差异，可用于鉴别诊断。
