Başdelioğlu Koray, Toksöz Yıldırım Ayşe Nur, Reddy Krishna, Özkan Korhan
Orthopaedics and Traumatology, Yeditepe University Faculty of Medicine, Istanbul, TUR.
Pathology, Istanbul Medeniyet University Göztepe Training and Research Hospital, Istanbul, TUR.
Cureus. 2022 Apr 17;14(4):e24197. doi: 10.7759/cureus.24197. eCollection 2022 Apr.
Bizarre parosteal osteochondromatous proliferation (BPOP) or Nora's lesion is a rare, benign, but locally aggressive tumor. We present a case of a 45-year-old patient with progressive swelling of his toe for four years, pain, and difficulty with shoe wear. The lesion was excised after adequate evaluation and the resection histopathology was compatible with Nora's lesion. There was no local recurrence at 24 months of follow-up. Nora's lesion can be effectively treated by complete surgical excision or en bloc resection. Though rare, Nora's lesion should be considered in the differential diagnoses of osteogenic and/or chondrogenic overgrowths in the bones of feet such as subungual exocytosis, osteochondroma, chondrosarcoma, periosteal chondroma/chondrosarcoma, and parosteal osteosarcoma.
奇异型骨旁骨软骨瘤样增生（BPOP）或诺拉氏病损是一种罕见的、良性但具有局部侵袭性的肿瘤。我们报告一例45岁患者，其脚趾渐进性肿胀4年，伴有疼痛及穿鞋困难。经充分评估后切除病损，切除组织病理学检查结果符合诺拉氏病损。随访24个月时无局部复发。诺拉氏病损可通过完整手术切除或整块切除得到有效治疗。尽管罕见，但在足部骨骼成骨性和/或软骨性过度生长的鉴别诊断中，如甲下外生性骨疣、骨软骨瘤、软骨肉瘤、骨膜软骨瘤/软骨肉瘤及骨旁骨肉瘤，应考虑诺拉氏病损。
