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使用Amplatzer血管封堵器对肺动静脉畸形进行血管内栓塞术

Endovascular Embolisation of Pulmonary Arteriovenous Malformation Using Amplatzer Vascular Plugs.

作者信息

Muhammad Azeemuddin, Rauf Zainab, Shahid Jehanzeb, Iqbal Junaid, Haq Tanveer U, Zafar Uffan

机构信息

Department of Radiology, Aga Khan University Hospital, Karachi, PAK.

Department of Radiology, Dow University of Health Sciences, Karachi, PAK.

出版信息

Cureus. 2022 Apr 17;14(4):e24214. doi: 10.7759/cureus.24214. eCollection 2022 Apr.

Abstract

Pulmonary arteriovenous malformation (PAVMs) are abnormal communications between pulmonary arteries and veins. The rarity of their occurrence, coupled with the risks they pose, including brain abscess, embolic stroke, and myocardial infarction, mandates that they should not be overlooked in the differential diagnosis of patients presenting with haemoptysis, dyspnea, clubbing, cyanosis, hypoxemia, or epistaxis. We present the case of a 41-year-old local female who presented to our hospital as an outpatient with decreased oxygen saturation (SpO) of 70%-80% for the past two years with a final diagnosis of PAVM. The initial baseline workup showed polycythemia with a hemoglobin level of 19 mg/dL and raised hematocrit. She had extensive workup in the past two years for her polycythemia including gene mutation testing and cardiac workup which all turned out normal. Her chest X-ray (CXR) showed right lung opacity which was initially considered to be infective but it did not respond to antibiotic treatment. Later on, a CT scan of the chest was performed and findings were typical of a large PAVM which had two feeding arteries. The patient was referred to a cardiothoracic surgeon who sent the patient to the interventional radiology section for endovascular management. The embolization procedure was then performed and both feeders were successfully embolised. After the procedure, the patient's SpO levels were restored to 95%-96%, and no post-procedure complications were noted.

摘要

肺动静脉畸形(PAVM)是肺动脉与静脉之间的异常交通。其发病率低,再加上它们带来的风险,包括脑脓肿、栓塞性中风和心肌梗死,这就要求在对咯血、呼吸困难、杵状指、发绀、低氧血症或鼻出血患者进行鉴别诊断时不能忽视它们。我们报告一例41岁的当地女性患者,她因过去两年氧饱和度(SpO)降至70%-80%前来我院门诊就诊,最终诊断为PAVM。初始的基线检查显示红细胞增多症,血红蛋白水平为19mg/dL,血细胞比容升高。过去两年她针对红细胞增多症进行了广泛检查,包括基因突变检测和心脏检查,结果均正常。她的胸部X线(CXR)显示右肺有不透明影,最初认为是感染性的,但对抗生素治疗无反应。后来进行了胸部CT扫描,结果显示为典型的大型PAVM,有两条供血动脉。该患者被转诊至心胸外科医生处,后者将患者送至介入放射科进行血管内治疗。随后进行了栓塞手术,两条供血动脉均成功栓塞。术后,患者的SpO水平恢复到95%-96%,未发现术后并发症。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5d11/9113524/6174bf0a9865/cureus-0014-00000024214-i01.jpg

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