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Long-Term Outcomes of Laparoscopic Distal Gastrectomy for Locally Advanced Gastric Cancer: The KLASS-02-RCT Randomized Clinical Trial.腹腔镜辅助进展期胃癌根治术的长期疗效:KLASS-02 RCT 随机临床试验。
J Clin Oncol. 2020 Oct 1;38(28):3304-3313. doi: 10.1200/JCO.20.01210. Epub 2020 Aug 20.
2
Prolonged postoperative ileus in gastric surgery: Is there any difference between laparoscopic and open surgery?胃手术后的长时间术后肠梗阻:腹腔镜手术与开放手术有区别吗?
Cancer Med. 2019 Sep;8(12):5515-5523. doi: 10.1002/cam4.2459. Epub 2019 Aug 5.
3
Association Between Compliance to an Enhanced Recovery Protocol and Outcome After Elective Surgery for Gastric Cancer. Results from a Western Population-Based Prospective Multicenter Study.增强恢复方案的依从性与胃癌择期手术治疗结局的相关性。一项基于西方人群的前瞻性多中心研究结果。
World J Surg. 2019 Oct;43(10):2490-2498. doi: 10.1007/s00268-019-05068-x.
4
Does Atelectasis Cause Fever After Surgery? Putting a Damper on Dogma.肺不张会导致术后发热吗?对传统观念说“不”。
JAMA Surg. 2019 May 1;154(5):375-376. doi: 10.1001/jamasurg.2018.5645.
5
Effect of Laparoscopic Distal Gastrectomy vs Open Distal Gastrectomy on Long-term Survival Among Patients With Stage I Gastric Cancer: The KLASS-01 Randomized Clinical Trial.腹腔镜远端胃切除术与开腹远端胃切除术治疗Ⅰ期胃癌患者的长期生存效果比较:KLASS-01 随机临床试验。
JAMA Oncol. 2019 Apr 1;5(4):506-513. doi: 10.1001/jamaoncol.2018.6727.
6
Equivalent feasibility and safety of perioperative care by ERAS in open and laparoscopy-assisted distal gastrectomy for gastric cancer: a single-institution ancillary study using the patient cohort enrolled in the JCOG0912 phase III trial.加速康复外科在开腹和腹腔镜辅助远端胃癌根治术中围手术期管理的等效可行性和安全性:一项使用 JCOG0912 三期临床试验入组患者队列的单中心辅助研究。
Gastric Cancer. 2019 May;22(3):617-623. doi: 10.1007/s10120-018-0873-3. Epub 2018 Sep 7.
7
Multimodal Enhanced Recovery After Surgery (ERAS) Program is the Optimal Perioperative Care in Patients Undergoing Totally Laparoscopic Distal Gastrectomy for Gastric Cancer: A Prospective, Randomized, Clinical Trial.多模态加速康复外科(ERAS)方案是行完全腹腔镜远端胃癌根治术患者的最佳围手术期护理:一项前瞻性、随机、临床试验。
Ann Surg Oncol. 2018 Oct;25(11):3231-3238. doi: 10.1245/s10434-018-6625-0. Epub 2018 Jul 26.
8
Insurance status, inhospital mortality and length of stay in hospitalised patients in Shanxi, China: a cross-sectional study.中国山西住院患者的保险状况、住院死亡率及住院时间:一项横断面研究
BMJ Open. 2017 Aug 1;7(7):e015884. doi: 10.1136/bmjopen-2017-015884.
9
Enhanced Recovery After Surgery: A Review.术后加速康复:综述。
JAMA Surg. 2017 Mar 1;152(3):292-298. doi: 10.1001/jamasurg.2016.4952.
10
Enhanced recovery care after colorectal surgery in elderly patients. Compliance and outcomes of a multicenter study from the Spanish working group on ERAS.老年患者结直肠手术后的强化康复护理。西班牙加速康复外科工作组多中心研究的依从性和结果
Int J Colorectal Dis. 2016 Sep;31(9):1625-31. doi: 10.1007/s00384-016-2621-7. Epub 2016 Jul 4.

腹腔镜远端胃切除术中术后加速康复方案的实际依从率

Actual compliance rate of Enhanced Recovery After Surgery protocol in laparoscopic distal gastrectomy.

作者信息

Park Sang Hyeok, Kang So Hyun, Lee Sang Jun, Won Yongjoon, Park Young Suk, Ahn Sang-Hoon, Suh Yun-Suhk, Park Do Joong, Kim Hyung-Ho

机构信息

Department of Surgery, Seoul National University Bundang Hospital, Seongnam, Korea.

Department of Surgery, Seoul National University College of Medicine, Seoul, Korea.

出版信息

J Minim Invasive Surg. 2021 Dec 15;24(4):184-190. doi: 10.7602/jmis.2021.24.4.184.

DOI:10.7602/jmis.2021.24.4.184
PMID:35602855
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8965987/
Abstract

PURPOSE

The Enhanced Recovery After Surgery (ERAS) protocol enhances recovery rate after laparoscopic distal gastrectomy (LDG). An ERAS protocol has been applied to most patients who underwent LDG at our center. In this study, we determined the actual compliance rate of the ERAS protocol and analyzed the risk factors for noncompliance.

METHODS

Medical records of 1,013 patients who underwent LDG from March 2016 to December 2017 were reviewed retrospectively. The compliance group (A) included 327 patients who were discharged within four days postoperatively. The noncompliance group (B) comprised 686 patients who were not discharged within four days postoperatively.

RESULTS

The compliance rate of the ERAS protocol was 32.3%. Potential compliance rate was 53.2%. Most common reasons for noncompliance were fever (n = 115) and ileus (n = 111). The 30-day emergency room visit rate was significantly lower in group A than that in group B ( = 0.006). Median age, American Society of Anesthesiologists (ASA) physical status classification, operation time, and pathologic stage were significantly higher in group B than those in group A ( < 0.001, < 0.001, = 0.005, and < 0.001, respectively). Risk factors for noncompliance were ASA classification of ≥III (odds ratio [OR], 2.251; = 0.007), age of ≥70 years (OR, 1.572; = 0.004), operation time of ≥180 minutes (OR, 1.475; = 0.003), and pathologic stage of ≥III (OR, 2.224; < 0.001).

CONCLUSION

The current ERAS protocols should be applied to patients without risk factors.

摘要

目的

术后加速康复(ERAS)方案可提高腹腔镜远端胃癌切除术(LDG)后的恢复率。我们中心大多数接受LDG的患者都采用了ERAS方案。在本研究中,我们确定了ERAS方案的实际依从率,并分析了不依从的危险因素。

方法

回顾性分析2016年3月至2017年12月期间接受LDG的1013例患者的病历。依从组(A组)包括327例术后4天内出院的患者。不依从组(B组)包括686例术后4天内未出院的患者。

结果

ERAS方案的依从率为32.3%。潜在依从率为53.2%。不依从的最常见原因是发热(n = 115)和肠梗阻(n = 111)。A组的30天急诊就诊率显著低于B组( = 0.006)。B组的中位年龄、美国麻醉医师协会(ASA)身体状况分级、手术时间和病理分期均显著高于A组(分别为 < 0.001、< 0.001、 = 0.005和 < 0.001)。不依从的危险因素包括ASA分级≥III(比值比[OR],2.251; = 0.007)、年龄≥70岁(OR,1.572; = 0.004)、手术时间≥180分钟(OR,1.475; = 0.003)和病理分期≥III(OR,2.224; < 0.001)。

结论

当前的ERAS方案应应用于无危险因素的患者。