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Caution in using second generation tyrosine kinase inhibitor, especially for first line therapy of chronic myeloid leukemia.

作者信息

Gambacorti-Passerini Carlo, Nicolini Franck Emmanuel, Larson Richard A, Aroldi Andrea, Fontana Diletta, Piazza Rocco, le Coutre Philipp, Antolini Laura, Assouline Sarit

机构信息

Hematology Division, ASST Monza, Monza, Italy.

University of Milano-Bicocca, Monza, Italy.

出版信息

Am J Hematol. 2022 Aug;97(8):E296-E298. doi: 10.1002/ajh.26618. Epub 2022 Jun 9.

DOI:10.1002/ajh.26618
PMID:35604243
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9543833/
Abstract
摘要

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[III. Chronic myeloid leukemia-effectiveness of second generation tyrosine kinase inhibitors for first line treatment of chronic myeloid leukemia-].[III. 慢性髓性白血病——第二代酪氨酸激酶抑制剂用于慢性髓性白血病一线治疗的有效性-]
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本文引用的文献

1
Tyrosine Kinase Inhibitor discontinuation in Chronic Myeloid Leukemia: eligibility criteria and predictors of success.酪氨酸激酶抑制剂在慢性髓性白血病中的停药：适应证标准和成功预测因素。
Am J Hematol. 2022 Aug;97(8):1075-1085. doi: 10.1002/ajh.26556. Epub 2022 Apr 12.
2
Adverse outcomes in chronic myeloid leukemia patients treated with tyrosine kinase inhibitors: Follow-up of patients diagnosed 2002-2017 in a complete coverage and nationwide agnostic register study.酪氨酸激酶抑制剂治疗的慢性髓性白血病患者的不良结局：在一项全覆盖且全国性的未知登记研究中对 2002-2017 年确诊的患者进行随访。
Am J Hematol. 2022 Apr;97(4):421-430. doi: 10.1002/ajh.26463. Epub 2022 Jan 20.
3
Second malignancies in patients with myeloproliferative neoplasms: a population-based cohort study of 9379 patients.骨髓增殖性肿瘤患者的二次恶性肿瘤：一项基于人群的 9379 例患者的队列研究。
Leukemia. 2018 Oct;32(10):2203-2210. doi: 10.1038/s41375-018-0027-y. Epub 2018 Jan 30.
4
Cardiovascular toxicities of BCR-ABL tyrosine kinase inhibitors in chronic myeloid leukemia: preventive strategies and cardiovascular surveillance.慢性髓性白血病中BCR-ABL酪氨酸激酶抑制剂的心血管毒性：预防策略与心血管监测
Vasc Health Risk Manag. 2017 Aug 4;13:293-303. doi: 10.2147/VHRM.S108874. eCollection 2017.
5
Life Expectancy of Patients With Chronic Myeloid Leukemia Approaches the Life Expectancy of the General Population.慢性髓性白血病患者的预期寿命接近普通人群。
J Clin Oncol. 2016 Aug 20;34(24):2851-7. doi: 10.1200/JCO.2015.66.2866. Epub 2016 Jun 20.
6
First-line treatment of 102 chronic myeloid leukemia patients with imatinib: a long-term single institution analysis.102 例慢性髓性白血病患者伊马替尼一线治疗：长期单中心分析。
Am J Hematol. 2014 Oct;89(10):E184-7. doi: 10.1002/ajh.23804. Epub 2014 Jul 31.
7
Deep molecular response is reached by the majority of patients treated with imatinib, predicts survival, and is achieved more quickly by optimized high-dose imatinib: results from the randomized CML-study IV.大多数接受伊马替尼治疗的患者达到了深度分子反应，该反应可预测生存，并且通过优化的高剂量伊马替尼更快实现：来自随机 CML-研究 IV 的结果。
J Clin Oncol. 2014 Feb 10;32(5):415-23. doi: 10.1200/JCO.2013.49.9020. Epub 2013 Dec 2.
8
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Blood. 2011 Dec 15;118(25):6515-20. doi: 10.1182/blood-2011-04-348755. Epub 2011 Oct 28.
9
Multicenter independent assessment of outcomes in chronic myeloid leukemia patients treated with imatinib.多中心独立评估伊马替尼治疗慢性髓性白血病患者的结局。
J Natl Cancer Inst. 2011 Apr 6;103(7):553-61. doi: 10.1093/jnci/djr060. Epub 2011 Mar 21.
10
Are chronic myeloid leukemia patients more at risk for second malignancies? A population-based study.慢性髓性白血病患者发生第二恶性肿瘤的风险更高吗？一项基于人群的研究。
Am J Epidemiol. 2010 Nov 1;172(9):1028-33. doi: 10.1093/aje/kwq262. Epub 2010 Sep 22.