From the Department of Cardiology, Westchester Medical Center and New York Medical College, Valhalla, NY.
Department of Internal Medicine, University of Central Florida College of Medicine, Orlando, FL.
Cardiol Rev. 2023;31(2):93-98. doi: 10.1097/CRD.0000000000000460. Epub 2022 May 23.
Infective endocarditis (IE) after transcatheter aortic valve implantation (TAVI) is a rare but potentially fatal event. In this systematic review, we searched PubMed and Embase for large TAVI studies and registries to identify the incidence, presentation, microbiology, risk factors, and outcomes of IE in this population. After application of the selection criteria and quality assessment, 8 studies representing 255,310 TAVR cases and 4218 cases of IE qualified for this review. IE following TAVI is uncommon with an incidence of 0.87 to 1.7 events per 100 person-years. Most events occur in the first year following valve implantation. Staphylococcus , Enterococcus , and Streptococcus species are the most common pathogens. Risk factors include age, sex, concomitant comorbidities, and procedural factors. Outcomes are dismal, and surgical intervention is rare in this population.
经导管主动脉瓣植入术(TAVI)后感染性心内膜炎(IE)是一种罕见但潜在致命的事件。在这项系统评价中,我们检索了 PubMed 和 Embase 中的大型 TAVI 研究和注册中心,以确定该人群中 IE 的发生率、表现、微生物学、危险因素和结局。在应用选择标准和质量评估后,有 8 项研究代表了 255310 例 TAVR 病例和 4218 例 IE,符合本综述的条件。TAVI 后 IE 并不常见,发病率为每 100 人年 0.87 至 1.7 例。大多数事件发生在瓣膜植入后的第一年。金黄色葡萄球菌、肠球菌和链球菌是最常见的病原体。危险因素包括年龄、性别、并存的合并症和程序因素。结局较差,该人群中很少进行手术干预。