Niwa K, Tanaka T, Mori H, Takahashi M
Jpn J Clin Oncol. 1987 Mar;17(1):95-100.
A case of extramedullary plasmacytoma originating from the upper mediastinum is described. Its pathologic, cytologic and immunohistopathologic findings were distinctive. The neoplastic cells had dense bodies in the cytoplasm. Neither M-protein in the serum nor Bence Jones protein in the urine was detected. However, cellular IgG, having a lambda-type light chain was shown, by immunohistochemical staining following trypsin digestion, to be present in the tissue sections.
本文描述了一例起源于上纵隔的髓外浆细胞瘤。其病理、细胞学及免疫组织病理学表现具有独特性。肿瘤细胞的细胞质内有致密小体。血清中未检测到M蛋白，尿中也未检测到本周蛋白。然而，经胰蛋白酶消化后进行免疫组织化学染色显示，组织切片中存在具有λ型轻链的细胞IgG。
