Pharmaceutical and Biologically-Active Compounds Research Laboratory, Department of Chemistry, Iran University of Science and Technology, Tehran, 16846-13114, Iran.
Sci Rep. 2022 May 23;12(1):8642. doi: 10.1038/s41598-022-10774-z.
In this research, cellulose grafted to chitosan by EDTA (Cs-EDTA-Cell) bio-based material is reported and characterized by a series of various methods and techniques such as FTIR, DRS-UV-Vis, TGA, FESEM, XRD and EDX analysis. In fact, the Cs-EDTA-Cell network is more thermally stable than pristine cellulose or chitosan. There is a plenty of both acidic and basic sites on the surface of this bio-based and biodegradable network, as a multifunctional organocatalyst, to proceed three-component synthesis of 2-amino-4H-pyran derivatives at room temperature in EtOH. The Cs-EDTA-Cell nanocatalyst can be easily recovered from the reaction mixture by using filtration and reused for at least five times without significant decrease in its catalytic activity. In general, the Cs-EDTA-Cell network, as a heterogeneous catalyst, demonstrated excellent catalytic activity in an environmentally-benign solvent to afford desired products in short reaction times and required simple experimental and work-up procedure compared to many protocols using similar catalytic systems.
在这项研究中，报道了通过 EDTA 将纤维素接枝到壳聚糖上的生物基材料（Cs-EDTA-Cell），并通过一系列不同的方法和技术进行了表征，如 FTIR、DRS-UV-Vis、TGA、FESEM、XRD 和 EDX 分析。事实上，Cs-EDTA-Cell 网络比原始纤维素或壳聚糖具有更高的热稳定性。这种生物基和可生物降解的网络表面存在大量的酸性和碱性位，可用作多功能有机催化剂，在室温下在 EtOH 中进行三组分 2-氨基-4H-吡喃衍生物的合成。Cs-EDTA-Cell 纳米催化剂可以通过过滤从反应混合物中容易地回收，并在至少五次重复使用中没有明显降低其催化活性。总的来说，Cs-EDTA-Cell 网络作为一种多相催化剂，在环境友好的溶剂中表现出优异的催化活性，与许多使用类似催化体系的协议相比，它可以在短反应时间内提供所需的产物，并且需要简单的实验和后处理程序。
