Nie Guangming, Bai Zhimin, Chen Juan, Yu Wenying
State Key Laboratory Base of Eco-chemical Engineering, College of Chemistry and Molecular Engineering, Qingdao University of Science and Technology, Qingdao 266042, People's Republic of China.
ACS Macro Lett. 2012 Nov 20;1(11):1304-1307. doi: 10.1021/mz300341h. Epub 2012 Oct 19.
A nanostructure composite material consisting of poly(indole-6-carboxylic acid) (PICA) and carboxylic groups ended multiwall carbon nanotubes (MWNTs) was directly electrosynthesized from indole-6-carboxylic acid (ICA) monomer and MWNTs in one step, in which MWNTs was also used as supporting electrolytes. And a simple electrochemical sensor for recognition of target DNA related to hepatitis B virus (HBV) was directly fabricated by means of this composite material. The corresponding detection limit is 2.0 fmol L. This interesting conducting polymer with a very large surface area will provide new insights into how a biosensor is designed.
由聚（吲哚 - 6 - 羧酸）（PICA）和羧基封端的多壁碳纳米管（MWNTs）组成的纳米结构复合材料，是通过一步法由吲哚 - 6 - 羧酸（ICA）单体和MWNTs直接电合成的，其中MWNTs还用作支持电解质。并且利用这种复合材料直接制备了一种用于识别与乙型肝炎病毒（HBV）相关的目标DNA的简单电化学传感器。相应的检测限为2.0 fmol/L。这种具有非常大表面积的有趣导电聚合物将为生物传感器的设计提供新的思路。
