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经皮颈椎间盘成形术治疗神经根型颈椎病的长期临床疗效:一项回顾性队列研究

Long-Term Clinical Results of Percutaneous Cervical Nucleoplasty for Cervical Radicular Pain: A Retrospective Cohort Study.

作者信息

de Rooij Judith Divera, Gadjradj Pravesh Shankar, Aukes Hans, Groeneweg George, Speksnijder Caroline Margina, Huygen Frank Johannes

机构信息

Department of Anesthesiology, Center for Pain Medicine, Erasmus MC University Medical Center, Rotterdam, the Netherlands.

Department of Orthopedics, Physiotherapy Unit, Erasmus MC University Medical Center, Rotterdam, the Netherlands.

出版信息

J Pain Res. 2022 May 17;15:1433-1441. doi: 10.2147/JPR.S359512. eCollection 2022.

Abstract

PURPOSE

Percutaneous cervical nucleoplasty (PCN) is a minimally invasive treatment for cervical radicular pain due to a disc herniation. Preliminary results show equivalent patient-reported outcomes of PCN as compared to conventional anterior cervical discectomy. However, there is a paucity of long-term outcome data. Therefore, the primary objective of this study is to investigate the long-term clinical results of PCN.

PATIENTS AND METHODS

A retrospective analysis was conducted on patients who underwent PCN at a secondary referral center between 2010 and 2014. Before surgery and five days after surgery, numeric rating scales (NRS) for arm pain and neck pain and data on complications were collected. To determine long-term follow-up outcomes, patients were sent a questionnaire booklet containing the Core Outcome Measures Index-Neck (COMI-Neck), NRS for arm pain and neck pain, Likert-scales on patient satisfaction and questions regarding the incidence of reoperations and complications.

RESULTS

The baseline characteristics were collected for 158 patients. At a median follow-up of 41.5 months (interquartile range (IQR) 27.0 to 57.5), data were available for 118 patients (74.7%). At short-term follow-up, patients that underwent PCN had a mean decrease of 3.0 on the NRS for arm pain (95% CI 2.5 to 3.6) compared to baseline, while at long-term follow-up, a mean decrease of 2.8 (95% CI 1.0 to 3.6) was observed. At the long-term follow-up, 67.8% of the patients were fully recovered from all symptoms and 93.3% remained satisfied with the PCN treatment results. The reoperation rate for recurrent disc herniation was 21.4% at long-term follow-up.

CONCLUSION

PCN appears to be a safe and effective treatment at short-term and long-term follow-up of a specific selection of cervical herniated discs, with an acceptable long-term reoperation rate. These study results suggest a potential role of PCN as a less invasive treatment option for cervical radicular pain due to a soft disc herniation, before anterior cervical discectomy should be considered.

摘要

目的

经皮颈椎间盘成形术(PCN)是一种治疗因椎间盘突出导致的颈神经根性疼痛的微创治疗方法。初步结果显示,与传统的前路颈椎间盘切除术相比,患者报告的PCN治疗效果相当。然而,长期疗效数据较少。因此,本研究的主要目的是调查PCN的长期临床结果。

患者与方法

对2010年至2014年间在一家二级转诊中心接受PCN治疗的患者进行回顾性分析。在手术前和手术后五天,收集手臂疼痛和颈部疼痛的数字评分量表(NRS)以及并发症数据。为了确定长期随访结果,向患者发送了一本问卷手册,其中包含核心结局指标指数-颈部(COMI-Neck)、手臂疼痛和颈部疼痛的NRS、患者满意度的李克特量表以及关于再次手术发生率和并发症的问题。

结果

收集了158例患者的基线特征。在中位随访41.5个月(四分位间距(IQR)27.0至57.5)时,有118例患者(74.7%)的数据可用。在短期随访中,接受PCN治疗的患者与基线相比,手臂疼痛的NRS平均下降3.0(95%CI 2.5至3.6),而在长期随访中,观察到平均下降2.8(95%CI 1.0至3.6)。在长期随访中,67.8%的患者所有症状完全缓解,93.3%的患者对PCN治疗结果仍感到满意。在长期随访中,复发性椎间盘突出的再次手术率为21.4%。

结论

对于特定选择的颈椎间盘突出症患者,PCN在短期和长期随访中似乎是一种安全有效的治疗方法,长期再次手术率可接受。这些研究结果表明,在考虑前路颈椎间盘切除术之前,PCN作为一种侵入性较小的治疗颈神经根性疼痛的选择可能具有一定作用。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a843/9123892/97e3a328a779/JPR-15-1433-g0001.jpg

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