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青少年急性心肌炎致冠状动脉痉挛:1 例报告。

Coronary artery spasm due to acute myocarditis in an adolescent: a case report.

机构信息

Department of Pediatrics, Pusan National University Yangsan Hospital, 20, Geumo-ro, Mulgeum-eup, Yangsan-si, Gyeongsangnam-do, 50612, South Korea.

Department of Radiology, Pusan National University Yangsan Hospital, Yangsan-si, 50612, South Korea.

出版信息

BMC Pediatr. 2022 May 24;22(1):304. doi: 10.1186/s12887-022-03354-7.

Abstract

BACKGROUND

Myocarditis refers to the inflammation of the myocardium caused by infection or autoimmune disease that may or may not present with clinical manifestations, such as gastrointestinal symptoms, dyspnea, chest pain, or sudden death. Although myocarditis and coronary artery vasospasm may mimic ST-segment elevation myocardial infarction (STEMI) with normal coronary arteries on angiography, acute myocarditis rarely causes coronary artery spasm. Here, we report a case of coronary artery spasm with reversible electrocardiographic changes mimicking STEMI in an adolescent with acute myocarditis.

CASE PRESENTATION

A 15-year-old boy present with sudden-onset repeated chest pain following a 3-day history of flu-like illness. Cardiac biomarkers were significantly elevated. Electrocardiography showed ST-segment elevation in the absence of detectable vasospasm on coronary angiography. These findings were consistent with the diagnosis of coronary artery spasm secondary to acute myocarditis. Treatment with immunoglobulin for 2 days improved his condition. The patient was discharged on the 12th day with complete resolution of symptoms and normalization of electrocardiogram findings.

CONCLUSIONS

We reported a case of coronary artery spasm due to acute myocarditis. This study highlights the importance of considering coronary artery spasm due to acute myocarditis as a differential diagnosis in patients presenting with signs of STEMI as these diseases have different medical management strategies.

摘要

背景

心肌炎是指由感染或自身免疫性疾病引起的心肌炎症,可能有也可能没有临床表现,如胃肠道症状、呼吸困难、胸痛或猝死。尽管心肌炎和冠状动脉血管痉挛在血管造影时可能与正常冠状动脉的 ST 段抬高型心肌梗死(STEMI)相似,但急性心肌炎很少引起冠状动脉痉挛。在这里,我们报告了一例冠状动脉痉挛伴可逆性心电图改变的病例,该患者为急性心肌炎,表现为 STEMI 样。

病例介绍

一名 15 岁男孩在流感样疾病发作 3 天后突然出现反复胸痛。心脏生物标志物明显升高。心电图显示 ST 段抬高,冠状动脉造影未发现可检测到的血管痉挛。这些发现与急性心肌炎继发的冠状动脉痉挛的诊断一致。用免疫球蛋白治疗 2 天,病情改善。第 12 天,患者出院,症状完全缓解,心电图恢复正常。

结论

我们报告了一例由急性心肌炎引起的冠状动脉痉挛的病例。本研究强调了在出现 STEMI 迹象的患者中考虑由急性心肌炎引起的冠状动脉痉挛作为鉴别诊断的重要性,因为这些疾病有不同的治疗策略。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/86dc/9128271/57c720c60d66/12887_2022_3354_Fig1_HTML.jpg

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