Kim Nayoung, Choi Young-Jin, Na Jae Yoon, Oh Jae-Won
Department of Pediatrics, Hanyang University Seoul Hospital, Seoul 04763, South Korea.
Department of Pediatrics, Hanyang University Guri Hospital, Guri-si 11923, South Korea.
World J Clin Cases. 2022 Apr 6;10(10):3170-3177. doi: 10.12998/wjcc.v10.i10.3170.
To the best of our knowledge, cases of Kawasaki disease (KD) occurring at the age of 12 are rare, even in Asia where the incidence of KD is high. We report a case of lymph-node-first presentation of KD (NFKD) in a 12-year-old girl with () infection who presented with prolonged fever and lymphadenitis refractory to macrolide antibiotics.
A previously healthy 12-year-old girl presented with fever, myalgia, sore throat, swelling, and tenderness on the right side of the neck. She was initially diagnosed with lymphadenitis caused by refractory to macrolide antibiotics. She had elevated brain natriuretic peptide (BNP) levels. Finally, the patient was diagnosed with KD. After receiving intravenous immunoglobulin, the fever resolved, and her symptoms improved.
NFKD should be differentiated from adolescent lymphadenitis presenting with prolonged fever by checking the BNP level early.
据我们所知，12岁发生川崎病（KD）的病例罕见，即便在KD发病率较高的亚洲地区亦是如此。我们报告一例12岁女童以淋巴结首发表现的川崎病（NFKD），该女童有（）感染，表现为持续发热和对大环内酯类抗生素难治的淋巴结炎。
一名既往健康的12岁女童出现发热、肌痛、咽痛、颈部右侧肿胀及压痛。她最初被诊断为由对大环内酯类抗生素难治的（）引起的淋巴结炎。她的脑钠肽（BNP）水平升高。最终，该患者被诊断为川崎病。接受静脉注射免疫球蛋白后，发热消退，症状改善。
应通过早期检查BNP水平，将NFKD与表现为持续发热的青少年淋巴结炎相鉴别。
