Brainard G C, Knobler R L, Podolin P L, Lavasa M, Lublin F D
Life Sci. 1987 Mar 30;40(13):1319-26. doi: 10.1016/0024-3205(87)90589-3.
Groups of adult male Syrian hamsters were kept in a long photoperiod (LD 14:10) or a short photoperiod (LD 10:14). After 12 weeks, half of the animals in each light:dark cycle were immunized with an immunogenic amino acid polymer. Exposure to short photoperiod was associated with a significant reduction in testicular, accessory sex organ, splenic and brown fat weights. However, photoperiod length did not influence whole body, thymic, adrenal or kidney weights. Spleens of immunized animals in the long photoperiod were significantly heavier than those of unimmunized animals in the long photoperiod, and both were heavier than spleens from immunized or unimmuized animals in the short photoperiod. This reflected increased splenic lymphocyte and macrophage counts. However, there was no difference in antibody production between animals kept in different photoperiods. These results demonstrate that the daily photoperiod length affects both hamster reproductive competence as well as selected immune parameters (splenic weight and mononuclear cell hyperplasia) but does not alter antibody production.
将成年雄性叙利亚仓鼠分组，分别饲养在长光照周期（LD 14:10）或短光照周期（LD 10:14）环境中。12周后，每个光照/黑暗周期中的一半动物用免疫原性氨基酸聚合物进行免疫。暴露于短光照周期与睾丸、附属生殖器官、脾脏和棕色脂肪重量显著降低有关。然而，光照周期长度并未影响全身、胸腺、肾上腺或肾脏的重量。长光照周期中免疫动物的脾脏明显重于长光照周期中未免疫动物的脾脏，且两者均重于短光照周期中免疫或未免疫动物的脾脏。这反映出脾脏淋巴细胞和巨噬细胞数量增加。然而，饲养在不同光照周期的动物之间抗体产生没有差异。这些结果表明，每日光照周期长度既影响仓鼠的生殖能力，也影响特定的免疫参数（脾脏重量和单核细胞增生），但不会改变抗体产生。
