Ghent University, Belgium.
European Institute for Innovation through Health Data, Belgium.
Stud Health Technol Inform. 2022 May 25;294:377-381. doi: 10.3233/SHTI220478.
In this study representation of chemical substances in IDMP is reviewed, with an exploration of aggregation levels for substance used in the virtual drug data models of RxNorm, SNOMED-CT, ATC/INN, and the Belgian SAM database, for products with a single substance and combinations of substances. Active moiety and available solid states forms are explored for diclofenac, amoxicillin, carbamazepine, amlodipine, with regard to their representation in coding systems such as WHODrug, SMS, UNII, CAS, and SNOMED-CT. By counting the number of medicinal products in Belgium for amlodipine in each level of aggregation, concepts for grouper of substances and two levels of grouper of medicinal products are illustrated. Recommendations are made for the further development of IDMP and its link to international drug classifications.
本研究回顾了 IDMP 中化学物质的表示法，并探讨了用于 RxNorm、SNOMED-CT、ATC/INN 和比利时 SAM 数据库虚拟药物数据模型的物质的聚合级别，这些物质用于具有单一物质和物质组合的产品。本文探讨了双氯芬酸、阿莫西林、卡马西平、氨氯地平的活性部分和可用的固体状态形式，以及它们在 WHODrug、SMS、UNII、CAS 和 SNOMED-CT 等编码系统中的表示。通过统计比利时每种聚合级别的氨氯地平的药品数量，说明了物质分组器和药品分组器两级的概念。为进一步开发 IDMP 及其与国际药物分类的联系提出了建议。
