Iten Léa, Carroz Patrice, Domenichini Giulia, Graf Denis, Herrera Claudia, Le Bloa Mathieu, Monney Pierre, Porretta Alessandra, Pascale Patrizio, Pruvot Étienne, Teres Cheryl
Service de cardiologie, Centre hospitalier universitaire vaudois, 1011 Lausanne.
Rev Med Suisse. 2022 May 25;18(783):1048-1051. doi: 10.53738/REVMED.2022.18.783.1048.
Atrial fibrillation (AF) is the most common arrhythmia encountered in adults; it is associated with a significant morbidity and mortality. Obesity is a risk factor contributing to AF occurrence. Recently, interest has focused on epicardial adipose tissue (EAT), defined as a fatty deposit located between the epicardium and the visceral pericardium. Its characteristics are distinct from classic adipose deposits: it infiltrates the epicardial myocardium and secretes cytokines, which modulate cardiomyocyte electrophysiology and cardiac remodeling. Different studies show that EAT can be an independent risk factor for AF and that EAT thickness, as measured by CT or MRI, could predict the presence, severity and recurrence of AF.
心房颤动（AF）是成人中最常见的心律失常；它与显著的发病率和死亡率相关。肥胖是导致AF发生的一个危险因素。最近，人们的兴趣集中在心脏外膜脂肪组织（EAT）上，它被定义为位于心外膜和脏层心包之间的脂肪沉积物。其特征与经典的脂肪沉积物不同：它浸润心外膜心肌并分泌细胞因子，这些细胞因子可调节心肌细胞电生理和心脏重塑。不同的研究表明，EAT可能是AF的一个独立危险因素，并且通过CT或MRI测量的EAT厚度可以预测AF的存在、严重程度和复发情况。
