Slaaf D W, Tangelder G J, Teirlinck H C, Reneman R S
Microvasc Res. 1987 Jan;33(1):71-80. doi: 10.1016/0026-2862(87)90008-2.
Spontaneous arteriolar vasomotion and its relation to arterial pressure reduction was studied in the rabbit tenuissimus muscle using intravital microscopy. Vasomotion was observed in all transverse arterioles and their first-order side branches. Vasomotion frequency ranged from 5 to 32 cycles per minute (median: 25 cpm). The relative vasomotion amplitude in transverse arterioles varied from 0.06 to 0.44 (median: 0.22). Vasomotion was generally of the on-off type in first-order side branches. A gradual reduction in arterial pressure as achieved by aortic occlusion resulted in an abrupt disappearance of vasomotion. Vasomotion disappeared between 19 and 59 mm Hg (median: 30.4 mm Hg). No differences were found between the pressures at which vasomotion ceased in transverse arterioles and first-order side branches. With a further reduction of arterial pressure transverse arterioles attained a maximal diameter of 98-265% (median: 119%) of the maximal diameter during vasomotion. After release of occlusion vasomotion reappeared much earlier in the first-order side branches than in their feeding transverse arterioles. It is concluded that although vasomotion influences capillary perfusion, it does not play a major role in the adaptation of vascular resistance following a reduction in arterial pressure.
采用活体显微镜技术，在兔薄肌中研究了小动脉的自发血管运动及其与动脉压降低的关系。在所有横行小动脉及其一级侧支中均观察到血管运动。血管运动频率为每分钟5至32次循环（中位数：25次/分钟）。横行小动脉的相对血管运动幅度在0.06至0.44之间（中位数：0.22）。一级侧支中的血管运动通常为开关型。通过主动脉阻断使动脉压逐渐降低，导致血管运动突然消失。血管运动在19至59毫米汞柱之间消失（中位数：30.4毫米汞柱）。横行小动脉和一级侧支中血管运动停止时的压力之间未发现差异。随着动脉压进一步降低，横行小动脉的最大直径达到血管运动期间最大直径的98%至265%（中位数：119%）。阻断解除后，一级侧支中的血管运动比其供血横行小动脉更早重新出现。结论是，虽然血管运动影响毛细血管灌注，但在动脉压降低后血管阻力的适应过程中它并不起主要作用。
