Possanza Casey Catherine M, Moore Jeffrey S
Departments of Chemistry and §Materials Science and Engineering, and ‡Beckman Institute of Advanced Science and Technology, University of Illinois at Urbana-Champaign, Urbana, Illinois 61801, United States.
Departments of Chemistry and Materials Science and Engineering, and ‡Beckman Institute of Advanced Science and Technology, University of Illinois at Urbana-Champaign, Urbana, Illinois 61801, United States.
ACS Macro Lett. 2016 Nov 15;5(11):1257-1260. doi: 10.1021/acsmacrolett.6b00698. Epub 2016 Oct 31.
A series of poly(vinyl ester sulfone)s are synthesized and are found to rapidly degrade in the presence of base. Solution phase NMR indicates that the sensitivity of these polymers to base depends on the identity of the ester functional group of the polymers. From most to least sensitive these are poly(vinyl chloroacetate sulfone) > poly(vinyl acetate sulfone) > poly(vinyl benzoate sulfone) > poly(vinyl pivalate sulfone). Significantly, these polymers were more reactive to base than the aliphatic poly(1-hexene sulfone). Additionally, degradation of these polymers in bulk occurs rapidly with exposure to aqueous solutions of base. The polymers are stable in water and possess good barrier properties; films of 30 μm thickness allow on average <1% crossover of dye over 7 days. Based on the data collected, poly(vinyl ester sulfone) polymers are promising for use in microcapsules, in particular, for applications where sustained or staged release would benefit from a series of different microcapsule compositions.
合成了一系列聚（乙烯基酯砜），发现它们在碱存在下会迅速降解。溶液相核磁共振表明，这些聚合物对碱的敏感性取决于聚合物酯官能团的特性。从最敏感到最不敏感依次为聚（氯乙烯乙酸酯砜）＞聚（乙酸乙烯酯砜）＞聚（苯甲酸乙烯酯砜）＞聚（新戊酸乙烯酯砜）。值得注意的是，这些聚合物对碱的反应性比脂肪族聚（1-己烯砜）更高。此外，这些聚合物在本体中暴露于碱水溶液时会迅速降解。这些聚合物在水中稳定且具有良好的阻隔性能；30μm厚的薄膜在7天内平均染料渗透率＜1%。基于所收集的数据，聚（乙烯基酯砜）聚合物有望用于微胶囊，特别是在一系列不同微胶囊组合物有利于持续或分阶段释放的应用中。
