Department of Neurology, Krankenhaus Lindenbrunn, Coppenbrügge, Germany.
Faculty of Medicine, University of Münster, Germany.
Cephalalgia. 2022 Oct;42(11-12):1294-1298. doi: 10.1177/03331024221099220. Epub 2022 May 25.
Visual snow syndrome is a phenomenon for which no effective treatment is known. It is highly comorbid with migraine, therefore we performed a retrospective chart review of patients with visual snow syndrome treated with a monoclonal antibody against calcitonin gene related peptide or its receptor.
We enrolled 15 patients with visual snow syndrome who received at least once a monoclonal antibody against calcitonin gene related peptide or its receptor. None of the patients reported relief of visual snow syndrome whereas those patients with comorbid migraine reported a very good efficacy of the antibody against the migraine headache but not against the migraine aura.
The data suggest that visual snow syndrome is not mediated by calcitonin gene related peptide in a relevant way and that the calcitonin gene related peptide receptor is not involved in the network underlying the visual snow syndrome.
视觉雪综合征是一种现象，目前尚无有效的治疗方法。它与偏头痛高度共病，因此我们对接受降钙素基因相关肽单克隆抗体或其受体治疗的视觉雪综合征患者进行了回顾性图表审查。
我们招募了 15 名患有视觉雪综合征的患者，他们至少接受了一次降钙素基因相关肽单克隆抗体或其受体的治疗。没有患者报告视觉雪综合征缓解，而那些伴有偏头痛共病的患者报告了针对偏头痛头痛的抗体非常有效，但对偏头痛先兆无效。
数据表明，视觉雪综合征不是通过降钙素基因相关肽以相关方式介导的，并且降钙素基因相关肽受体不参与视觉雪综合征的基础网络。
