Nagl W
Naturwissenschaften. 1987 Jan;74(1):30-4. doi: 10.1007/BF00367038.
Recent models for the organization of the chromosomes of eukaryotes in mitosis and interphase are discussed with respect to their condensation hierarchy. Possible functional interpretations are indicated. At present, an alternating coiling and loop formation, induced by histones and nonhistone proteins, respectively, appears to be the most probable structure. The relationship of DNA properties to chromatin structure and function is also briefly discussed.
本文讨论了真核生物染色体在有丝分裂和间期的组织的最新模型,涉及它们的凝聚层次结构。文中指出了可能的功能解释。目前,分别由组蛋白和非组蛋白诱导的交替螺旋和环形成似乎是最可能的结构。还简要讨论了DNA特性与染色质结构和功能的关系。